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Okazaki fragments

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Okazaki fragments
DNA replication for the lagging strand is discontinuous and away from the replication fork. The small fragments synthesized are called Okazaki fragments and later stitched together by DNA Ligase.
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Okazaki Fragments

The resulting fragments are called Okazaki fragments.
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Okazaki fragments Small fragments of DNA (approximately 1000 nucleotides) that are formed on the lagging strand at the replication fork of DNA synthesis and later joined; enable 5' .

Okazaki fragments - short lengths of DNA produced on the lagging strand during DNA replication
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For the band, see Okazaki Fragments (band).
DNA replication
An Okazaki fragment is a relatively short fragment of DNA (with an RNA primer at the 5' terminus) created on the lagging strand during DNA replication.

Pol III lengthens the bursts, forming Okazaki fragments. Pol I then "reads" the fragments, removes the RNA, and adds its own nucleotides (this is necessary because RNA and DNA use slightly different kinds of nucleotides).

Then, as the replication fork nears the end of the DNA, there is no longer enough template to continue forming Okazaki fragments. So the 5' end of each newly-synthesized strand cannot be completed.

Primase
An enzyme that synthesizes ribonucleotide primers for lagging strand DNA synthesis of Okazaki fragments. Polymerizes ribonucleotide triphosphates in the 5' to 3' direction.

Since the DNA strands are antiparallel, and replication proceeds in thje 5' to 3' direction on EACH strand, one strand will form a continuous copy, while the other will form a series of short Okazaki fragments.

See also: Okazaki fragment, Strand, DNA replication, Origin, Replication

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