[edit] Orthology
Homologous sequences are orthologous if they were separated by a speciation event: when a species diverges into two separate species, the divergent copies of a single gene in the resulting species are said to be orthologous.
Orthology
Describes the evolutionary origin of a locus. Loci in two species are said to be orthologous when they have arisen from the same locus of their common ancestor.
For example, gene A in species 1 and 2 are orthologous.
" White observed that sequence generation and annotation are coupled tightly and that people generating sequence should be enhancing their submissions with data such as database and orthology matches.
Homology
Similarities in DNA or protein sequences between individuals of the same species or among different species. These two types of homology are called paralogy and orthology.
See also the figure at NCBI.
 See also: Chromosome, Nucleotide, Species, Sequence, DNA
  
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