Peptidyl transferase center A region of the large ribosomal subunit that catalyzes peptide-bond formation between the aminoacyl (or peptidyl) trna in the P site and the aminoacyl trna in the A site.
"Ribosome structure and activity are altered in cells lacking snoRNPs that form pseudouridines in the peptidyl transferase center". Molecular Cell 11 (2): 425-435. ^ Salazar M, Fedoroff OY, Miller JM, Ribeiro NS, Reid BR (1992).
Interaction of the RF with a stop codon causes the peptidyl transferase activity of the ribosome to catalyze the hydrolysis of the ester bond between the tRNA and the polypeptide chain, ...
See also: Genetic material, Nucleotide, G protein, Insertion, Polymerase
 
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