Peripheral protein

Peripheral proteins
Attached to integral membrane proteins, or associated with peripheral regions of the lipid bilayer.

peripheral protein A protein on the surface of a biological membrane.
peripheral Structure or location distant from center, near outer boundaries.
periproct Region of aboral plates around the anus of echinoids.

They have large sections embedded in the hydrophobic (middle) layer of the membrane. Peripheral proteins are not bonded as strongly to the membrane. They may just sit on the surface of the membrane, anchored with a few hydrogen (H) bonds.

See also: Membrane, Cell, Membranes, Molecule, Lipid