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Phagocytes

Biology PhagocytePhagocytosis

phagocytes White blood cells that can engulf (by phagocytosis) and destroy microorganisms including viruses and bacteria; cells in this category include neutrophils and monocytes.

 


Phagocytes ("phago-"=eating, "cyte"=cell) migrate to affected areas and engulf pathogens. Neutrophils and macrophages are phagocytic white blood cells. This migration of white blood cells causes the redness and inflammation associated with infection.

Phagocytes are attracted by chemotaxis
Opsonisation by antibodies (bacteria becomes coated with antibody)
As a result, binding between bacteria and phagocytes is improved
Phagocytes form pseudopodia around the particle ...

"Antimicrobial functions of mononuclear phagocytes". J Immunol Methods 174 (1-2): 185-94. PMID 8083520.
^ May R, Machesky L (2001). "Phagocytosis and the actin cytoskeleton". J Cell Sci 114 (Pt 6): 1061-77. PMID 11228151.

Human neutrophils are white blood cells that serve as professional phagocytes: their primary function is to eat and kill bacteria and they arrive quickly at the site of a bacterial infection.

Using phagocytic cells, like macrophages and neutrophils, to gain entry into the internal environment is a risky strategy because phagocytes are poised to destroy engulfed bacteria.

destruction of foreign materials by the action of phagocytes (white blood corpuscles)
Source: Noland, George B. 1983. General Biology, 11th Edition. St. Louis, MO. C. V. Mosby
...

Pseudopods also capture prey phagocytosis. Phagocytosis pseudopods have arisen in a number of different protist groups, but also in some cells (phagocytes) in multicellular organisms.
Morphology ...

Clumping makes the job of phagocytes easier, as they will more readily engulf bacteria in clumps. Bound antibodies sometimes serve as tags, called opsonins, enhancing phagocytosis.

The T cells secrete proteins that punch holes in the infected cell's plasma membrane. The infected cell's cytoplasm leaks out, the cell dies, and is removed by phagocytes. Killer T cells may also bind to cells of transplanted organs.

The specialized cells in our blood are the red blood cells (rbcs) containing the respiratory protein, hemoglobin, to carry gases, the white blood cells (e.g., phagocytes, lymphocytes) which fight infection and the blood platelets which upon ...

See also: Phagocyte, Cell, Cells, Organ, Bacteria

Biology PhagocytePhagocytosis

 
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