polygenic
determined by many genes at different loci, with small additive effects
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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Definition of polygenic :
a character controlled by many genes.
Polygenic Trait
A polygenic trait is one whose phenotype is influenced by more than one gene. Traits that display a continuous distribution, such as height or skin color, are polygenic.
polygenic inheritance
(pol-ee-jen-ik) [Gk. polus, many + genos, race, descent]
An additive effect of two or more gene loci on a single phenotypic character.
polygyny ...
polygenic inheritance Occurs when a trait is controlled by several gene pairs; usually results in continuous variation. PICTURE ...
Polygenic disorder: Genetic disorder resulting from the combined action of alleles of more than one gene (e.g., heart disease, diabetes, and some cancers).
polygenic inheritance The inheritance of a characteristic which is determined by the cumulative actions of many different genes, each with small individual effects.
Polygenic. Controlled by or associated with more than one gene.
Polylinker. A short DNA sequence containing several re- striction enzyme recognition sites that is contained in cloning vectors.
Polygenic Inheritance
A polygenic trait is due to more than one gene locus. It involves active and inactive alleles.
Active alleles function additively.
Polygenic
Controlled by or associated with more than one gene. Cf monogenic.
Related Terms:
Gene
The term coined by Johannsen (1909) for the fundamental physical and functional unit of heredity.
Polygenic inheritance is a pattern responsible for many features that seem simple on the surface. Many traits such as height, shape, weight, color, and metabolic rate are governed by the cumulative effects of many genes.
polygenic inheritance. Inheritance of traits influenced by multiple alleles; traits show continuous variation between extremes; offspring are usually intermediate between the two parents; also known as blending and quantitative inheritance.
On a pedigree, polygenic diseases do tend to 'run in families', but the inheritance does not fit simple patterns as with Mendelian diseases. But this does not mean that the genes cannot eventually be located and studied.
See polygenic disorders.
Complementation
The process by which two recessive mutants can supply each other's deficiency, ...
A disorder which is caused by mutations in just one gene (such as haemophilia), as opposed to polygenic disorders (such as hypertension) which involve the interaction of several genes.
Source : PhRMA Genomics
Mutation ...
Many traits are multifactorial. This means they are controlled by genes at several loci which may be additive (polygenic) and other genes and the environment also play a role in the expression of the trait.
Nicely explained in Falconer's polygenic threshold model for dichotomous nonmendelian characters in Human Molecular Genetics. See also a Lecture Note by Dr R Tissot. For an example see a paper by Wanstrat & Wakeland.
 See also: Human, Organ, Inheritance, Environment, Gene
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