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Hopfield, worked on error correction in Transcription and Translation (kinetic proof-reading), and associative memory models (Hopfield net)
Martin Karplus, research on molecular dynamical simulations of biological macromolecules.
And thanks to the precision of the process (which includes a "proof-reading" function), the job is done with only about one incorrect nucleotide for every 109 nucleotides inserted. In other words, more often than not, the E.
 See also: Enzyme, Action, Protein, Human, Polymerase
  
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