Regulatory region or sequence: A DNA base sequence that controls gene expression.
Resolution: Degree of molecular detail on a physical map of DNA, ranging from low to high.
Regulatory region
A DNA base sequence that controls gene expression.
Related Terms:
Base sequence
The order of nucleotide bases in a DNA molecule. Length is usually defined as the number of base pairs. Cf. sequence, DNA sequence.
Regulatory region
A DNA base sequence that controls gene expression.
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A regulatory region a short distance upstream from the 5' end of a transcription start site that acts as the binding site for RNA polymerase. A region of DNA to which RNA polymerase binds in order to initiate transcription.
All genes have regulatory regions in addition to regions that explicitly code for a protein or RNA product.
Changes in the regulatory region of the human gene for the V1a receptor have been linked to autism.
Oxytocin
Oxytocin is a peptide of 9 amino acids.
It acts on certain smooth muscles: ...
Genetic constructs that include regulatory regions targeting gene expression to specific tissues are necessary if the gene product is to be harvested readily.
Slowed translation through a regulatory region allows formation of a RNA secondary structure that promotes transcription termination. Requires coupled transcription and translation and thus is restricted to prokaryotes.
Promoters represent critical elements that can work in concert with other regulatory regions (enhancers, silencers, boundary elements /insulators) to direct the level of transcription of a given gene.
Promoter sequences ...
Effects of point mutations: Point mutations in junk DNA are common but have no effect. Sometimes point mutations in regulatory regions have no effect and sometimes they alter the expression of some genes.
Additions and deletions ...
The knowledge obtained from the sequences applies to everyone because all humans share the same basic set of genes and genomic regulatory regions that control the development and maintenance of their biological structures and processes.
For example, it can be used to find all occurances of a given cis regulatory region in upstream sequences, or to find all proteins having a similar domain.
a mutation of the lactose operator that is no longer able to bind the lac I gene product which codes for the lac repressor. How would the expression of the lac Z be regulated in the resulting cells that are diploid for the lactose regulatory region ...
 See also: DNA, Sequence, Gene, Express, Trans
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