Response element Response elements are binding sites for transcription factors. Sequences of response elements are required for the functions of the transcription factors.
Iron-response element (IRE) A stem-loop structure found in the mrnas for ferritin and transferrin receptor that interacts with the IRE-binding protein and regulates the translation of the mrnas.
Response element: By definition, a "response element" is a portion of a gene which must be present in order for that gene to respond to some hormone or other stimulus. Response elements are binding sites for transcription factors.
The response element is part of the promoter of a gene. Binding by the receptor activates or represses, as the case may be, the gene controlled by that promoter. It is through this mechanism that steroid hormones turn genes on (or off).
[15] These cytoplasmic and nuclear molecules may include transcription factors such as cAMP response element binding protein (CREB).
In a variety of organisms, including flies (Drosophila) and humans, one enzyme, CREB (cyclic-AMP response element binding protein), seems to be involved in the steps that facilitate this new protein expression.
AP-1 activation through EGFR was assessed using a β-lactamase reporter gene ... An AP-1 response element (TGACTAA, 7X) was inserted into the MCS of the β ... Full article ...
See also: Transcription, Transcript, Trans, Transcription factor, Protein
 
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