Ribozymes for Human Therapy
The ability of ribozymes to recognize and cut specific RNA molecules makes them exciting candidates for human therapy.
Ribozyme Inactivation of Target Gene Expression
Another method of determining gene function is to begin with an interesting cellular function and work back to the gene. Jack Barber's team at Immusol, Inc.
ribozyme
An enzymatic RNA molecule that catalyzes reactions during RNA splicing.
RNA ...
Ribozyme. See Catalytic RNA.
Ribosomal RNA (rRNA). The RNA component of the ribosome. (See RNA.)
Ribosome. Cellular organelle that is the site of protein synthesis during translation. See Organelle, Translation.
Ribozymes
Ribozymes are molecules of RNA that function like enzymes, that is, they have an active site and increase the rate of specific chemical reactions.
Oxidation and Reduction Reactions ...
Ribozymes RNA molecules that display enzymatic activity.
Rickets A disease caused by the insufficient formation of vitamin D, resulting in the inadequate calcification of cartilage and bone.
Catalytic RNA (ribozyme). A natural or synthetic RNA molecule that cuts an RNA substrate. Cation. A positively charged ion. cDNA. DNA synthesized from an RNA template using reverse transcriptase. cDNA library.
"Structure, folding and mechanisms of ribozymes". Curr Opin Struct Biol 15 (3): 313-23. PMID 15919196.
^ Groves JT (1997). "Artificial enzymes. The importance of being selective". Nature 389 (6649): 329-30. PMID 9311771.
Ribozymes Information to link the RNA world to the DNA and RNA world. A summary of ribozymes by Access Excellence.
The RNA World (IMB Jena, Germany) Links to WWW RNA sites and resources. Lots of very cool images.
HIV and Other Retrovirus Sites (U.
Most organisms today use DNA as the hereditary material, although recent evidence (ribozymes) suggests that RNA may have been the first nucleic acid system to have formed. Nobel laureate Walter Gilbert refers to this as the RNA world.
Enzyme is usually a protein molecule with a characteristic sequence of amino acids that fold to produce a specific three-dimensional structure, which gives the molecule unique properties. Other molecule with catalytic activity is ribozyme, ...
The gene in question has a complex three-dimensional structure which is hypothesized to provide a chemical function necessary for viral propagation. (See ribozyme.) If so, most mutations would render it unfit for that purpose and would not propagate.
 See also: Protein, Trans, Proteins, Cells, Molecule
  
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