RNA interference (RNAi)
In testing the effects of antisense RNA, one should use sense RNA of the same coding region as a control. Surprisingly, preparations of sense RNA often turn out to be as effective an inhibitor as antisense RNA.
RNAi (RNA interference) The process of using small pieces of double-stranded RNA to reduce the activity of specific genes. The process occurs naturally in many organisms and is now commonly used in basic research.
RNA interference
gene knockout
transgenics and overexpression
mapping, cloning, and sequencing
gene expression ...
RNA interference.
Several types of RNA can downregulate gene expression by being complementary to a part of a gene.
RNA interference or gene silencing may be a new way to treat Huntington's. Short pieces of double-stranded RNA (short, interfering RNAs or siRNAs) are used by cells to degrade RNA of a particular sequence.
RNAi RNA interference (RNAi) is a method used to silence the expression of a target gene in order to determine the gene's function by analyzing the mutant phenotype.
RNAi: 'RNA interference' (a.k.a. 'RNA silencing') is the mechanism by which small double-stranded RNAs can interfere with expression of any mRNA having a similar sequence. Those small RNAs are known as 'siRNA', for short interfering RNAs.
One of these, WDFY2, appears to play an important role in early endocytosis and was revealed in a RNAi (RNA interference) screen in C. elegans. Interestingly, some proteins contain FYVE-like domains in C. elegans and D.
It turns out that what viruses are doing is interrupting certain processes that are normally required for defense. But these defense-like processes, like RNA silencing and RNA interference, are also involved in normal growth and development.
 See also: Interference, RNA, Trans, Gene, DNA
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