RNAi as a tool
In any case, the discovery of RNAi adds a promising tool to the toolbox of molecular biologists. Introducing dsRNA corresponding to a particular gene will knock out the cell's own expression of that gene. (Feeding C.
RNAi (RNA interference) The process of using small pieces of double-stranded RNA to reduce the activity of specific genes. The process occurs naturally in many organisms and is now commonly used in basic research.
RNAi RNA interference (RNAi) is a method used to silence the expression of a target gene in order to determine the gene's function by analyzing the mutant phenotype.
RNAi creates a specific knockout effect without actually mutating the DNA of interest. In C. elegans, RNAi has been used to systematically interfere with the expression of most genes in the genome.
RNAi: 'RNA interference' (a.k.a. 'RNA silencing') is the mechanism by which small double-stranded RNAs can interfere with expression of any mRNA having a similar sequence. Those small RNAs are known as 'siRNA', for short interfering RNAs.
One of these, WDFY2, appears to play an important role in early endocytosis and was revealed in a RNAi (RNA interference) screen in C. elegans. Interestingly, some proteins contain FYVE-like domains in C. elegans and D.
Another reverse genetics technique is the application of RNA interference. RNAi creates a specific knockout effect without actually mutating the DNA of interest. In C.
A technique for reducing gene expression without mutating the gene in the genome. Frequently used gene knock-down techniques include siRNA, RNAi, and antisense.
Related
Knock-Out RNAi siRNA ...
Usually associated with a technique used to knock out a gene's expression but does not knock out expression completely. RNAi is sometimes considered a knock down technique.
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For example, the format should allow a researcher to note the presence of RNAi results overlapping the region of interest.
 See also: Gene, Cells, Protein, DNA, Genome
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