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Rolling circle

Biology Rod cellsRoot cap

Rolling circle (sigma) replication
A type of DNA replication where a replication fork moves around a circular DNA molecule, producing a single-stranded concatamer (much like the way toilet paper peels off the roll).

 


Rolling circle replication is initiated by an initiator protein encoded by the plasmid or bacteriophage DNA.

Replication by rolling circle is common among bacteriophages and viruses in nature.

See the note under Drawbridge. Rolling circle of a paddle wheel, the circle described by the point whose velocity equals the velocity of the ship. Rolling fire, tackle used to steady the yards when the ship rolls heavily.

See also: Cells, Host, Replication, DNA, Strand

Biology Rod cellsRoot cap

 
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