Second Messengers
Second messengers are molecules that relay signals received at receptors on the cell surface — such as the arrival of protein hormones, growth factors, etc. — to target molecules in the cytosol and/or nucleus.
Second messenger system
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second messenger systems
systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter.
second messenger The mechanism by which nonsteroid hormones work on target cells.
second messenger
A small, nonprotein, water-soluble molecule or ion, such as calcium ion or cyclic AMP, that relays a signal to a cell's interior in response to a signal received by a signal receptor protein.
secondary compound ...
Second messenger A small signal molecule whose concentration changes in response to a primary messenger.
second messengers produced in one cell to rapidly diffuse into and stimulate events in surrounding cells.
C.
adjacent cells to form a water-tight barrier between their membranes.
Ca2+ as a second messenger
Ca2+ acts as a signal molecule within the cell. This works by tightly limiting the time and space when Ca2+ is free (and thus active).
A second messenger that regulates many intracellular reactions by transducing signals from extracellular growth factors to cellular metabolic pathways. Cytogenetics. Study that relates the appearance and behavior of chromosomes to genetic phenomenon.
We've been able to identify the ion channels and the second messenger cascades that are activated by opioids.
Nonsteroid hormones (water soluble) do not enter the cell but bind to plasma membrane receptors, generating a chemical signal (second messenger) inside the target cell.
be altered at a number of levels in AD post-mortem brains, including impaired agonist and G-protein regulation of phospholipase C, decreased protein kinase C (PKC) levels and activity, and a reduced number of receptor sites for the second messenger, ...
cAMP - cyclic 3',5' - adenosine monophosphate, an important intracellular second messenger molecule formed from ATP by the enzyme adenylate cyclase.
 See also: Cell, Protein, Trans, Membrane, Cells
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