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Sense mutation

nonsense mutation
a mutation that changes a codon from one that specifies an amino acid into one that does not; there are three such nonsense codons
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...

Nonsense Mutation
A nonsense mutation is the substitution of a single base pair that leads to the appearance of a stop codon where previously there was a codon specifying an amino acid.

Nonsense mutation
A mutation which replaces a codon for an amino acid with a codon for chain termination (UAG, UAA, or UGA).

nonsense mutation
A mutation that changes an amino acid codon to one of the three stop codons, resulting in a shorter and usually nonfunctional protein.
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A nonsense mutation is a point mutation in a sequence of DNA that results in a premature stop codon, or a nonsense codon in the transcribed mRNA, and possibly a truncated, and often nonfunctional protein product.
[edit] Point mutation ...

Nonsense mutation
Mutation that changes a codon or an amino acid to a termination or stop codon and leads to premature termination of translation.
Related Terms:
Mutation ...

MISSENSE MUTATION - A nucleotide mutation which results in a change in the amino acid sequence of the encoded protein (contrast with SILENT MUTATION).
MOBILITY SHIFT - See GEL SHIFT.

With a nonsense mutation, the new nucleotide changes a codon that specified an amino acid to one of the STOP codons (TAA, TAG, or TGA).

Missense mutation -- a change in the base sequence of a gene that alters or eliminates a protein. Mitochondrial DNA -- the mitochondrial genome consists of a circular DNA duplex, with 5 to 10 copies per organelle.

Three kinds of point mutations can occur. A mutation that results in an amino acid substitution is called a missense mutation.
A mutation that results in a stop codon so that incomplete proteins are produced, it is called a nonsense mutation.