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Sequence

Biology SepalsSequence homology

sequence
The noun: the order in which subunits appear in a chain, such as amino acids in a polypeptide or nucleotide bases in a dNA or rNA molecule.
The verb: To find out in what order the subunits appear in the chain.

 


Sequence Insights
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Insights Learned from the Human DNA Sequence ...

DNA sequence
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A DNA sequence (sometimes genetic sequence) is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, The possible letters are A, C, G, and T, ...

Simple Sequence Repeat (SSR)
Short, tandem repeats that are useful as genetic markers See also PCR Glossary.
Other Resources ...

a sequence that has been associated with rapidly degraded proteins
The short life-time of a protein is signaled by a region rich in the amino acids proline (P); glutamic acid (E); serine (S); or threonine (T).
Protein examples: Su(fu) ...

Sequencer: An apparatus used for deciphering the order of bases in a stra nd of DNA.
Sequencing: Determining of the order of bases in a DNA or RNA molecule.

sequence features Types of gene or genome features that can be mapped on the genome or a gene. These may be structural features of a gene, or characteristic sequence features of a genome (such as repeats or duplicated regions).

Sequence hypothesis. Francis Crick's seminal concept that genetic information exists as a linear DNA code; DNA and protein sequence are colinear.

Sequence templates Conserved residues that are structurally and functionally important and are characteristic of particular families of proteins.

The sequence of events
The cilia of the sensory neurons are immersed in a layer of mucus. Odorant molecules (molecules that we can smell) dissolve in the mucus and
bind to receptors on the cilia. These are "7-pass" transmembrane proteins.

DNA sequenced from 17-20 MY old magnolia
In the paper I explain here, the authors (Golenberg et. al., 1990) sequenced an 820 bp region (the rbcL gene) from the chloroplast DNA of a compression fossil of a magnolia.

Who sequenced the human genome?
Human Genome Project research was funded at many laboratories across the U.S. by the Department of Energy (DOE), the National Institutes of Health (NIH), or both. A list of the major U.S.

repeat sequences -- The length of a nucleotide sequence that is repeated in a tandem cluster.
replacement -- Fossilization process that occurs when an organism is completely decomposed and replaced by mineral.

Coding sequence That part of a gene which contains the codons which will, via a mRNA intermediate, be translated into polypeptide. Its antithesis is non-coding sequence.

Coding sequence (cds): The portion of a gene that is transcribed into mRNA and translated into protein.
Codominance: Equal effect on the phenotype of two alleles of the same locus (as opposed to recessive and dominant).

Sequence polymorphism differing in a single base pair.
Example for a single nucleotide substitution: ...

Sequence characterised amplified region (SCAR)
A locus representing a single RAPD fragment which has been sequenced. Primers specific to the locus can be designed and used in PCR amplification.
Related Terms:
Locus ...

Sequence comparison has also revealed that bacteria carry sections of DNA which seem to have come from other species in the evolutionarily recent past.

Sequences show the motility of this ciliated protozoan and the repetitious activity of both anterior and posterior contractile vacuoles.
5.4 Spirostomum (ciliated protozoa) ...

SEQUENCE POLYMORPHISM - See POLYMORPHISM.
SEQUENTIAL EPITOPE - See LINEAR EPITOPE.

A sequence of electron-carrier molecules (membrane proteins) that shuttle electrons during the redox reactions that release energy used to make ATP.
electronegativity
The tendency for an atom to pull electrons toward itself.

DNA sequence
The relative order of base pairs, whether in a fragment of DNA, a gene, a chromosome, or an entire genome. See base sequence.
Deletion
Loss of a segment of a chromosome as the genetical consequence of a transposition.

- A sequence located approximately 75 base-pairs upstream from eukaryotic transcription start sites. This sequence is one of those that enhance binding of RNA polymerase
Cacao ...

The sequence GAATTC appears three times in the DNA strand below. As a result, the strand is cut into four pieces.
Other restriction enzymes cut at different sites, some examples are listed below.
Enzyme ...

The sequence of amino acids is called its primary structure (the bonds between the amino acids are called peptide bonds) and the sequence is determined by the genetic code.

The sequence of this human genome was only a sequence of the referenced genome. And if you look at it alone, you could get the impression that the genome is some static thing that doesn't change.

Same sequence, the last of the 3 possible frames:
...AT GAC ATG TAA AGA TAG ACT AAC CTT TTG G.. ... Asp Met *** Arg *** Thr Asn Leu Leu ...

a DNA sequence anywhere on the same chromosome
D.
any DNA marker co-inherited with the genetic trait of interest ...

In consequence of the curve of the dental arch, terms such as anterior and posterior, as applied to the teeth, are misleading and confusing.

One consequence of this asexual method of reproduction is that all organisms in a colony are genetic equals.

The sequence of the genetic material of viruses coincides with the sequence of certain sections of DNA or RNA of host cells, ...

A short sequence (of RNA or DNA) from which DNA replication can initiate. May be either a synthetic DNA or RNA or a length of RNA synthesized in vivo by primase.

codon - sequence of three nucleotides in a DNA or messenger RNA molecule that represents the instruction for incorporation of a specific amino acid into a growing polypeptide chain.

codon A sequence of three bases on messenger RNA that specifies the position of an amino acid in a protein.
coefficient of relationship The fraction of genes identical by common descent shared between two individuals.

a new DNA sequence formed by the combination of two nonhomologous DNA molecules
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row
...

Flanking sequence or flanking region
The DNA sequence located on either side of a specific genetic locus.

codon A sequence of three nucleotides in messenger RNA that codes for a single amino acid.
coelom In animals, a body cavity between the body wall and the digestive system that forms during preadult development.

Microsatellite sequences are repetitive DNA sequences usually several base pairs in length. Microsatellite sequences are composed of non-coding DNA and are not parts of genes.

To ascertain the sequence (or particular order) of amino acid or nucleotide residues in a protein or nucleic acid ...

Cell cycle The sequence of events by which a cell duplicates its contents and divides in two.

Life Cycle: The sequence of events that occurs during the lifetime of an individual organism.
Maggot: The immature form (larva) of a fly or wasp, lacking legs and a well-developed head.

enhancer - DNA sequence in a gene that influences the gene's expression by increasing or decreasing its rate of RNA synthesis (via effects on binding and transcription of the basal transcription apparatus including RNA Polymerase); ...

Alternate forms of a gene or DNA sequence, which occur on either of two homologous chromosomes in a diploid organism. (See DNA polymorphism.) Alternative mRNA splicing. The inclusion or exclusion of different exons to form different mRNA transcripts.

Alu repetitive sequence -- the most common dispersed repeated DNA sequence in the human genome accounting for 5% of human DNA. The name is derived from the fact that these sequences are cleaved by the restriction endonuclease Alu.

Aerobic cells produce reactive oxygen species as a consequence of normal cellular metabolism, and an array of antioxidant systems are in place to maintain the redox balance.

Protein complexes that form kinetochores in the centromere regions of sister chromatids are attached to specific repetitive DNA sequences, known as satellite DNA, which are similar in each chromosome.

Food Chain: A linear sequence of organisms that exist on successive trophic levels within a natural community, through which energy is transferred by feeding.

"Blueprint" for protein synthesis that is transcribed from one strand of the DNA (gene) and which is translated at the ribosome into a polypeptide sequence.

Cells transcribe a DNA gene into an RNA version of the gene, and a ribosome then translates the RNA into a protein, a sequence of amino acids.

Mutation: Any inheritable change in DNA sequence.
Mutation breeding: Commonly used practices in plant breeding and other areas in which chemicals or radiation are applied to whole organisms, for example plants, ...

Gene: An ordered sequence of nucleotides which act as the functional subunit of hereditary information. The collection of genes in an organism determine the characteristics of that organism.

key (pest) - designates a pest category where management action is expected each season; also a means of identifying organisms by a hierarchical sequence of characters (dichotomous key) or separate lists of characters (synoptic key) used to ...

These include the comparisons of DNA sequences conducted within molecular biology or genomics, and comparisons of fossils or other records of ancient organisms in paleontology.

See also: DNA, Protein, Organ, Trans, Human