Sequencer: An apparatus used for deciphering the order of bases in a stra nd of DNA. Sequencing: Determining of the order of bases in a DNA or RNA molecule.
Automated sequencers can produce 7000 to 8000 bp of raw DNA sequence per day for each machine, with greater than 99% accuracy. Several laboratories have recently completed 100 kbp in several months and expect to complete l Mbp in the next year.
Using an automated DNA sequencer the DNA is read in 800bp lengths from both ends of each fragment.
Hood played a key factor in the Human Genome Project and was credited with developing the automated sequencer. He is recognized as one of the world's leading scientists in molecular biotechnology and genomics.
Several new methods are being developed and one is already commercially available (the Genome Sequencer 20 System). Its method is called pyrosequencing or sequencing by synthesis. It works like this.
For the sense of "sequencing" used in electronic music, see the music sequencer article.
See also: Sequence, DNA, Genome, Human, Sequencing
 
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