Sigma factor
A protein that functions as a subunit of bacterial RNA polymerases and is responsible for specificity of recognition of promoters. Different sigma factors allow recognition of different promoter sequences.
SIGMA FACTOR - Certain small ancillary proteins in bacteria that increase the binding affinity of RNA polymerase to a promoter. Different sigma factors recognize different promoter sequences.
Different sigma factors recognize different promoters and thus, the availability of sigma factors can regulate the transcription of genes associated with these promoters.
sigma factors used in prokaryotic transcription). (Raven 370)
Repressors bind to non-coding sequences on the DNA strand that are close to or overlapping the promoter region, impeding RNA polymerase's progress along the strand, ...
The binding of a promoter sequence (P) to a sigma factor-RNAP complex (R) is a two step process:
R+P ↔ RP(closed). K = 10E7
RP(closed) RP(open). K = 10E-2
Diseases Associated with Aberrant Promoter Function ...
 See also: Transcript, Nucleotide, Gene, Sequence, Polymerase
  
|
RSS
