Signal sequences A sequence of amino acid residues ranging in size from 13 to 36 residues, usually at the amino terminus of the nascent polypeptide chain, that marks the protein for translocation across the rough endoplasmic reticulum.
signal sequence
A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein.
The signal sequence consists of the first portion of the elongating polypeptide chain (so the signal sequence occurs at the amino terminal of the polypeptide). Typical signal sequences contain 15 - 30 amino acids.
The N-terminal signal sequence of the protein is recognized by a signal recognition particle (SRP) while the protein is still being synthesized on the ribosome.
Proteins that are transported by the ER and from there throughout the cell are marked with an address tag that are called a signal sequence.
AC transgene unit consists of a zeta-globin promoter fused to the v-Ha-ras structural gene with a terminal simian virus 40 (SV40) polyadenylation signal sequence.
Secreted protein
A protein that is exported through the cytoplasmic membrane. Most secreted proteins have specific signal sequences that promote interaction with the export apparatus in the membrane.
Segregrate
See segregration below.
Found in cells that are making proteins for export (enzymes, hormones, structural proteins, antibodies)
Thus, involved in protein synthesis
Modifies proteins by the addition of carbohydrates, removal of signal sequences ...
 See also: Trans, Sequence, Protein, Proteins, Cell
  
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