Single-gene disorder
Hereditary disorder caused by a mutant allele of a single gene (e.g., Duchenne muscular dystrophy, retinoblastoma, sickle cell disease).
See also: polygenic disorders
Somatic cell ...
Single-gene disorders are inherited in recognizable patterns: autosomal dominant, autosomal recessive, and X-linked. More information on the different modes of inheritance is available from the following Web sites: ...
Humans with single-gene disorders like
sickle-cell disease
hemophila
severe-combined immunodeficiency (SCID)
might have some of their cells ...
Although such disorders are inherited, they depend on the simultaneous presence of several alleles; thus the hereditary patterns are usually more complex than those of single-gene disorders. Compare single-gene disorders.
terms that initially seems a little odd, but in our own parlance--and geneticists have their own way of thinking about things--complex disease really is supposed to conjure up in your mind that this is not a simple Mendelian single-gene disorder.
 See also: Human, Genome, Gene, Cancer, DNA
  
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