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Biology  Solution hybridization  Somatic cell

pertaining to the body, for example, somatic mutation in which a stable gene change occurs in a body cell rather than in a germ (reproductive ) cell
Source: Noland, George B. 1983. General Biology, 11th Edition. St. Louis, MO. C. V. Mosby ...

somatic cell
Any plant or animal cell other than a germ cell or germ-cell precursor.

1. Pertaining to or characteristic of the soma or body.
2. Pertaining to the body wall in contrast to the viscera.

Related to the body. Pronounce:
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"Somatic cells" is a fairly general term which refers to essentially all the cells of the body except for the germ line; the germ line being the cells in the sexual organs that produce sperm and eggs. So anything that doesn't have the job of producing sperm or eggs is a somatic cell.

Given a somatic mono-allelic deletion M, the local admixture Adm.local is defined as the proportion of cells not harboring M (non-aberrant cells) over the total number of cells.

Somatic cell: These are all cells other than sex cells. Also called �body� cells.
Homologous: Having two of the same alleles on the same gene (one inherited from each parent such as 2 recessives or 2 dominants. (homo means the same) ...

Somatic Hypermutation (SHM) and Antibody Diversity
The diversifying mechanisms described above take place before the B cell encounters antigen.

Somatic cells: Any cell in the body except sex cells.
Template: a single DNA strand that serves as pattern for building a new second strand.
Thymine (T): A base; one of the molecular components of DNA and RNA. Always bonds with adenine (T-A).

somatic cell
[Gk. soma, body]
Any cell in a multicellular organism except a sperm or egg cell.
somatic nervous system ...

somatic Relating to the non-gonadal tissues and organs of an organism's body.
somatic cell A cell that is not or will not become a gamete; the cells of the body.
somatic senses All senses except vision, hearing, taste, and smell; include pain, temperature, and pressure.

Somatic cells: Cells of body tissues other than the germline.
Splicing: See gene splicing.
StarLinkTM: An insect-resistant variety of corn that was approved for animal feed only, not labeled for human consumption.

somatic cell gene therapy /sō-MAT-ək, -ik/ n. The incorporation new genetic material into somatic cells for therapeutic purposes. The new genetic material cannot be passed to offspring. See also: gene therapy.

somatic cell
any of the cells of a plant or animal except the reproductive cells.
Covered in BIOL1020 Lab 6 Mitosis & Meiosis ...

Somatic mutation. Mutation in the genome of a somatic cell. Somatic mutations are not germ-line transmitted, but are responsible for genetic events within a cell population, such as cancer cells.

somatic mesoderm [Gr. somatikos - of or for the body]. The cellular layer on the external side of the coelom; formed from the delamination of lateral plate mesoderm. In conjunction with somites, it will later form body wall and limbs.

Somatic gene therapy
In somatic gene therapy, the therapeutic genes are transferred into the somatic cells, or body, of a patient. Any modifications and effects will be restricted to the individual patient only, and will not be inherited by the patient's offspring or later generations.

Somatic cell gene therapy
Incorporating new genetic material into cells for therapeutic purposes. The new genetic material cannot be passed to offspring.
See also: gene therapy
Somatic cell genetic mutation ...

The somatic motor fibers spring from the cells of the nucleus ambiguus, which lies some distance from the surface of the rhomboid fossa in the lateral part of the medulla and is continuous below with the anterior gray column of the medulla spinalis.

The somatic (voluntary) and autonomic (involuntary) nervous system

Different areas of the nervous system are used for different types of nervous reaction: ...

[edit] Somatic cell gene therapy
In somatic cell gene therapy, the gene is introduced only in somatic cells, especially of these tissues in which expression of the concerned gene is critical for health.

sensory somatic system a subdivision of the peripheral nervous system that carries impulses from the external environment and the senses.
sepals modified leaves that enclose and protect a growing bud in flowers.
serum plasma from which clotting proteins have been removed.

Mutations: Somatic and Germinal, Single Gene and Chromosomal
P 68-73, 76-7, 316-35
T Ch 9, 16
Gene mutations, cancer, gonadal mosaicism and sporadics, polymorphisms, allelic and locus heterogeneity, VNTRs, STRs ...

Somatic hybrid
A hybrid cell line derived from fusion of cells from different sources. Human/rodent hybrids containing small amount of human genetic material such as a single chromosome are used in human gene mapping.
Related Terms:
Hybrid ...

Somatic cell
Any cell in the body except gametes and their precursors.
Related Terms:
Mature male or female reproductive cell (sperm or ovum) with a haploid set of chromosomes (23 for humans).

Somatic gene therapy can be broadly split in to two categories: ex vivo (where cells are modified outside the body and then transplanted back in again) and in vivo (where genes are changed in cells still in the body.) Recombination-based approaches in vivo are especially uncommon, ...

Somatic. Germ.
Problem : If a cell has a haploid number of 14 before DNA replication, what is the cell's diploid number after DNA replication has occurred?

Somatic growth. Growth of the body, exclusive of gametes
Sorting (of a sediment). The range of scatter of particle sizes about the median grain size of a sediment
Space limited. Description of a situation in which space is a limiting resource ...

somatic cell: Any cell in the body except gametes and their precursors. [DOE] Are the precursors stem cells?
All body cells, except the reproductive cells. NHGRI See also somatic cells Molecular Medicine ...

somatic cell Ordinary body cell; pertaining to or characteristic of a body cell. Any cell other than a germ cell or germ-cell precursor.
somatic mutation A mutation that occurs in cells of leaves, stems, or roots; a mutation occurring in any cells that are not involved in gamete formation.

The somatic nervous system includes the central and peripheral structures that make voluntary control of efferences. Central and peripheral structures that participate in the control of the vegetative (unconscious) functions of the body are included in the concept of visceral nervous system.

The somatic and autonomic nervous systems often cooperate in maintaining homeostasis.
Embryonic development of the vertebrate brain reflects its evolution from three anterior bulges of the neural tube.

Adult somatic stem cells can play critical roles in postembryonic developmental processes such as tissue renewal, growth, repair, and regeneration [1].

Problem 12: Somatic cell hybrids
By examining a number of somatic-cell hybrid lines for enzyme activities and their human chromosome constitution, scientists can determine
on which human chromosome the gene for a particular enzyme is located ...

Somatic cell
Any cell in the body except gametes and their precursors.
See also: gamete (ORNL)
Somatic cell gene therapy
Incorporating new genetic material into cells for therapeutic purposes. The new genetic material cannot be passed to offspring.
See also: gene therapy (ORNL) ...

somatic cell - all body cells except reproductive cells
gamete - reproductive cells (i.e. sperm & eggs)
chromosome - elongate cellular structure composed of DNA and protein - they are the vehicles which carry DNA in cells ...

Multicellular organisms are social organisms, different types of cells carry out different functions and only a small subset of cells, known as germ cells, give rise to the next generation of organisms. Other cells, known as somatic cells, form the body of the organism, ...

Somatic cells Any cell in the body except gametes and their precursors.
Southern blotting Transfer by absorption of DNA fragments separated in electrophoretic gels to membrane filters for detection of specific base sequences by radiolabeled complementary probes.

archeocyte - somatic cell of sponge that can differentiate into all three other cell types of the organism.
aster - radiating formation of microtubules at each pole of a spindle apparatus, formed during mitosis; comes from word meaning "star." ...

See Somatic cell. Germ cell (germ line) gene therapy. The repair or re- placement of a defective gene within the gamete-forming tissues, which produces a heritable change in an organism's genetic constitution. GMO. Genetically modified organism. Green revolution.

Barr body -- the condensed single X-chromosome seen in the nuclei of somatic cells of female mammals. base pair a pair of hydrogen-bonded nitrogenous bases (one purine and one pyrimidine) that join the component strands of the DNA double helix.

Synonymous with somatic chromosomes (chromosome pairs 1-22). Balanced polymorphismAn equilibrium of two or more alleles that has remained constant over long periods of time. Barr bodyThe sex chromatin, the visible inactive X chromosome on the somatic cell nuclear membrane.

Aneuploidy can affect the entire somatic cell population, as in trisomy 21 in which an extra chromosome results in Down Syndrome. Aneuploidy may also affect only certain cells.

The parietal lobe does a lot of analysis of touch which you think of us touch and in fact right where you go from parietal lobe to frontal lobe you have this ridge called the primary somatic motor, ...

Later a mutation occurs in the second copy of the gene in a somatic cell. In that cell both copies of the gene are mutated and the cell develops uncontrolled growth. An example of this is hereditary retinoblastoma, a serious cancer of the retina that occurs in early childhood.

Ward, W. S. and Coffey, D. S. (1991). DNA packaging and organization in mammalian spermatozoa: comparison with somatic cells. Biology of Reproduction 44, 569-574.
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Barr body: Also called sex-chromatin body, which represents the inactivated X chromosome in the nucleus of somatic mammalian cells. Normally only seen in female cells and not in male cells. It is the result of the process called dosage compensation.

A theory to account for the high degree of antibody variability found in population. The germ-line theory suggests that every B lymphocyte has all the genes for every type of immunoglobulin but transcribes only one. See somatic mutation theory.

See also: See also: Cells, Cell, Human, Trans, DNA

Biology  Solution hybridization  Somatic cell

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