STREPTAVIDIN - A bacterial analog of egg white avidin.
STRINGENCY - The conditions employed for hybridization which determine the specificity of the annealing reaction between two single-stranded nucleic acid molecules.
Biotin has an extraordinarily high affinity for streptavidin with a reported dissociation constant of ~10-15. This very strong binding affinity has made the biotin-streptavidin system very attractive for a multitude of in vitro labeling applications.
Important in fatty acid biosynthesis and catabolism and has found widespread use as a covalent label for macromolecules which may then be detected by high affinity binding of labelled avidin or streptavidin. Essential growth factor for many cells.
[125] Nanomechanical devices and algorithmic self-assembly have also been demonstrated,[126] and these DNA structures have been used to template the arrangement of other molecules such as gold nanoparticles and streptavidin proteins.[127] ...
 See also: Avidin, Sequencing, Enzyme, DNA, Sequence
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