TATA box. An adenine- and thymine-rich promoter sequence located 25-30 bp upstream of a gene, which is the binding site of RNA polymerase.
TATA box A conserved sequence 25 to 30 base pairs upstream from the site for transcription in many but not all genes; binding site for general factors involved in initiation of transcription. In prokaryotes the analogous is called Pribnow box.
TATA box: A sequence found in the promoter (part of the 5' flanking region) of many genes.
T2 virus[gene mapping] [Hershey-Chase experiment] T4 virus[rII locus] TACO (tryptophan-aspartate coat protein) Taenia solium Taiga Tanning TAP = Transporter associated with antigen processing Tapeworms Taste, in humans TATA box Tatum, E. L.
Usually associated with transcription-initiation regions of (housekeeping) genes transcribed at low rates that do not contain a TATA box.
most have the Goldberg Hogness or tATA box that is centred around position 25 and has the consensus sequence 5' TATAAAA 3'. Several promoters have a cAAT box around 90 with the consensus sequence 5' GGCCAATCT 3'.
Many eukaryotic promoters, but by no means all, contain a TATA box (sequence TATAAA), which in turn binds a TATA binding protein which assists in the formation of the RNA polymerase transcriptional complex.
Histones act in gene regulation. Histones can undergo posttranslational modifications. These modifications can play a role in gene regulation in an epigenetic manner. Regulation occurs at the TATA box.
See also: Sequence, Transcript, Trans, Promoter, Transcription
 
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