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Telomere

Biology TelomeraseTelophase

telomere
the tip of the chromosome arm
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...

 


Telomeres
Each eukaryotic chromosome consists of a single molecule of DNA associated with a variety of proteins.

Telomere
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Telomere. Along the chromosomes, which are long pieces of DNA...when you look at them as a picture, they look like lines. Well, the hard part is how to protect the ends of this line.

Telomere
The terminal part of a linear chromosome. Replication of the ends of linear DNA molecules requires specialized enzymes or structures.

telomere
The protective structure at each end of a eukaryotic chromosome. Specifically, the tandemly repetitive DNA (see Repetitive DNA) at the end of the chromosome's DNA molecule.
telophase ...

Telomere (TEE-lo-meer) A repetitive segment of DNA at the ends of eukaryotic chromosomes. Telomeres do not contain genes and, in the absence of telomerase, they shorten with each cell division.

Telomere: The end of a chromosome. This specialized structure is involved in the replication and stability of linear DNA molecules. See DNA replication.
Thymine (T): A nitrogenous base, one member of the base pair AT (adeninethymine).

Telomere The DNA structure which stabilises the ends of chromosomes.

Telomere. The end of a chromosome.
Template. An RNA or single-stranded DNA molecule upon which a complementary nucleotide strand is synthesized.

Telomeres
Shows the concept of how the ends of chromosomes, the telomeres, shorten each time the cell divides.
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Telomeres are restored to their original length by an enzyme called telomerase. This enzyme contains a single strand of RNA that is used to synthesize the telomeres.

Artificial chromosomeA vector constructed from host cell chromosomal elements such as origin of replication, telomeres and centromere (in eukaryotes).

Aging of this type is thought to be due to telomeres, regions at the tips of chromosomes which prevent genetic threads fraying every time a cell divides.

A yeast mini-chromosome used for cloning. It has telomeres, a centromere and an autonomous replication sequence (ARS). DNA fragments of 200-500 kb can be cloned using YAC vector.
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But the human chromosome 2 is the result of what is called a Robertsonian fusion - the ancestral ape chromosomes 2p and 2q appear to have fused at their ends (telomeres) to form the human chromosome 2 (Williams, not dated), ...

Originating from a bacterial plasmid; a YAC contains additionally a yeast centromeric region (CEN); a yeast origin of DNA replication (ARS); and two telomere regions (TEL). YACs are capable of cloning very large pieces of DNA.

Syndesis
= Synapsis. The conjugation or fusion of homologous chromosomesduring prophase of the first meiotic division, when crossing over occurs. Normally syndesis starts at the telomeres and passes on to the centromeres like a zipper.

The conjugation or fusion of homologous chromosomesduring prophase of the first meiotic division, when crossing over occurs. Normally syndesis starts at the telomeres and passes on to the centromeres like a zipper.

Genomic DNA in fragments of 200-500 kb are linked to sequences which allow them to propagate in yeast as a mini-chromosome (including telomeres, a centromere and an ARS - an autonomous replication sequence).

Heterochromatin tends to be most concentrated along chromosomes at certain regions of the structures, such as the centromeres and telomeres.

See also: Chromosome, DNA, Sequence, Human, Genome

Biology TelomeraseTelophase

 
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