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Transcription factor

Biology TranscriptionTranscription factors

Transcription factor synthesis Transcription factors (like all proteins) are transcribed from a gene on a chromosome into RNA, and then the RNA is translated into protein.

 


Transcription factor
Transcription factors are proteins that directly regulate the gene transcription machinery.
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transcription factor
(Science: molecular biology) protein required for recognition by rNA polymerases of specific stimulatory sequences in eukaryotic genes.

Transcription factors are extraordinarily diverse, but any one factor represents only a tiny fraction of the protein molecules present in the cell. This page describes how one can isolate and purify such rare molecules.

transcription factor
A regulatory protein that binds to DNA and stimulates transcription of specific genes.
transduction ...

transcription factor - DNA binding protein that turns genes on or off (regulates the level of transcription) by binding to enhancer elements in DNA and interacting with RNA polymerase at the promoter.

Transcription factor A protein that binds to regulatory regions and helps control gene expression.
Transcriptome The full complement of activated genes, mRNAs, or transcripts in a particular tissue at a particular time ...

Transcription factors are regulated by signals produced from other molecules. For example, hormones activate transcription factors and thus enable transcription. Hormones therefore activate certain genes.
Posttranscriptional Control ...

Transcription factor: A protein which is involved in the transcription of genes. These usually bind to DNA as part of their function (but not necessarily).

A transcription factor that enhances the production of inflammatory mediators.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...

The transcription factors that are coded for by segmentation genes regulate yet another family of developmental control genes, the homeotic selector genes. These genes exist in two ordered groups on Drosophila chromosome 3.

Transcription factor
sometimes, interactions between different proteins. Proteins called transcription factors bind to DNA sequences, known collectively as regulatory elements, located near the coding region of the gene in question
(Fig. 1).

Specialized transcription factories
Jon Bartlett, Jelena Blagojevic, David Carter, Christopher Eskiw, Maud Fromaget, Christy Job, Monee Shamsher, Inês Faro Trindade, Meng Xu and Peter R. Cook1 ...

Very often, these genes have transcription factors, which are proteins that bind to DNA, near these genes.

Pax genes code for (DNA binding) transcription factors. The paired box refers to a particular conserved DNA sequence that is shared by the different members of the Pax gene family.
Related Terms:
Gene ...

Examples include binding sites for transcription factors and splicing machinery.
Related Terms:
Nucleotide ...

Activation domain The structural region of a transcription factor that facilitates transcription in some manner. See also DNA-binding domain.
Active site A specific region of an enzyme that binds the substrate and carries out catalysis.

can require binding of multiple transcription factors to form a transcription complex
C.
have specific DNA sequences such as the "TATA" box that are recognized by proteins ...

binding site A DNA sequence to which a protein ,such as a transcription factor, binds.
Biological Replicate True for replicate hybridizations that use samples obtained from different RNA extracts from different biological material ...

Control elements: DNA sequences in genes that interact with regulatory proteins (such as transcription factors) to determine the rate and timing of expression of the genes as well as the beginning and end of the transcript.

CAAT box: A highly conserved DNA sequence found about 75 bp 5' to the site of transcription in eukaryotic genes. Its specific (trans-acting) transcription factor is CTF-1 (NF-1) (see also TATA / Goldberg-Hogness box).

Promoter The DNA sequences at the 5´ end of a gene which are responsible for binding RNA polymerase and transcription factors and which regulate the gene's expression.

reside and where most of the cellular metabolism occurs. Though mostly water, the cytosol is full of proteins that control cell metabolism including signal transduction pathways, glycolysis, intracellular receptors, and transcription factors.

See also: Transcription, Transcript, Trans, Protein, Gene