Transcription start site This is where a molecule of RNA polymerase II (pol II, also known as RNAP II) binds. Pol II is a complex of 12 different proteins (shown in the figure in yellow with small colored circles superimposed on it).
Transcription Start Site (TSS) Approximately -35 A binding site for RNA polymerase ...
Regions of DNA rich in CpG dinucleotides, also known as CpG islands, are often found upstream of the transcription start site in both tissue specific and housekeeping genes.
A sequence on DNA that functions as the RNA polymerase binding site, thus defining the transcription start site.
A regulatory region a short distance upstream from the 5' end of a transcription start site that acts as the binding site for RNA polymerase. A region of DNA to which RNA polymerase binds in order to initiate transcription.
Sequences on the 5' end of mRNA but not translated into protein. It extends from the transcription start site to just before the ATG translation initiation codon. 5' UTR may contain sequences that regulate translation efficiency or mRNA stability.
They are ubiquitous and interact with the core promoter region surrounding the transcription start site(s) of all class II genes.[8] ...
A region of DNA extending 150-300 bp upstream from the transcription start site that contains binding sites for RNA polymerase and a number of proteins that regulate the rate of transcription of the adjacent gene. (See Constitutive promoter.) ...
- A sequence located approximately 75 base-pairs upstream from eukaryotic transcription start sites. This sequence is one of those that enhance binding of RNA polymerase Cacao ...
Origin Short for origin of replication. The specific nucleotide sequence at which DNA synthesis is initiated. Cf. transcription start site and terminator.
Pribnow box Relatively invariant sequence of six nucleotides (consensus TATAAT) in prokaryotic promoters centred at the position minus 10 (10 base pairs upstream from the transcription start site). In eukaryotes the analogous is called TATA box.
generally take the form of associations of data such as genes, to keywords such as GO terms that describe the function, subcellular localization and processes involving the gene product. Structural annotations (e.g. transcription start sites, exons, ...
Pribnow box A promoter component of prokaryotic genes that has the consensus sequence 5'- TATAAA-3' located 10 base pairs downstream from the transcription start site.
upstream of the gene that might help enhance or repress the particular gene that's about to be transcribed in certain cell types. In general, if you think of the promoter as that piece of DNA that's just upstream of the transcription start site of a ...
See also: Transcription, DNA, Transcript, Trans, Sequence
 
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