Transformation has two meanings in molecular biology:
Transformation is the genetic alteration of a cell resulting from the introduction, uptake and expression of foreign DNA.
Transformation
For bacteria and yeasts, transformation refers to the techniques of introducing plasmid or other vectors into a host cell.
transformation
conversion of a normal cell into a cancerous cell; also refers to the uptake and incorporation of exogenous DNA by a cell
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
Transformation (genetics)
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Definition of transformation : ...
Transformation
Many bacteria can acquire new genes by taking up DNA molecules (e.g., a plasmid) from their surroundings. The ability to deliberately transform the bacterium E.
Transformation
Transfer of naked donor DNA into a cell.
Transformation frequency
The relative proportion of cells in a population that are transformed in a single experiment.
transformation In Grif?th's experiments with strains of pneumonia bacterium, the process by which hereditary information passed from dead cells of one strain into cells of another strain, ...
transformation
[L. trans, across + formare, to shape]
(1) The conversion of a normal animal cell to a cancerous cell. (2) A phenomenon in which external DNA is assimilated by a cell.
transgenic ...
Transformation: A process by which the genetic material carried by an individual cell is altered by incorporation of exogenous DNA into its genome.
Transformation. In prokaryotes, the natural or induced uptake and expression of a foreign DNA sequence--typically a recombinant plasmid in experimental systems.
Transformation involves the uptake of "naked" DNA (DNA not incorporated into structures such as chromosomes) by competent bacterial cells (Fig. 1).
transformation of bacteria by the recombinant DNA plasmids and selection using ampicillin .
E.
probing blots of bacteria clones with radioactive DNA complementary to the desired gene.
Transformation
- A change in the genetic structure of an organism as a result of the uptake and incorporation of foreign DNA.
Transgenic organism ...
transformation. Condition in which DNA in the environment of bacteria somehow penetrates them and is incorporated into their genetic complement, so that their progeny inherit the genetic characters so acquired.
transformation - morphological changes in a lymphocyte associated with the onset of division. Also used to denote the change to the autonomously dividing state of a cancer cell ...
TRANSFORMATION - Multiple meanings. With respect to cloning of DNA, refers to the transformation of bacteria (usually to specific antibiotic resistance) due to the uptake of foreign DNA.
Transformation (with respect to cultured cells): A change in cell morphology and behavior which is generally related to carcinogenesis.
TAC Transformation artificial chromosome used as a cloning vector for larger DNA fragments as well as for plant transformation.
Plasmids can transfer genes between bacteria and are important tools of transformation for genetic engineers. (See Nicked circle, pAMP, Relaxed plasmid, Stringent plasmid, Supercoiled plasmid.) Pleiotrophy.
TransformationUsually refers to passive uptake of DNA by cells, although in nature some bacterial species have a specific active uptake system.
Sol gel transformation (← links)
Vitreous humor (← links)
Fingerprints (← links)
Solation (← links)
Rocket immunoelectrophoresis (← links)
Carrier electrophoresis (← links)
Liesegang rings (← links)
Coagulates (← links) ...
In recent years oxidative stress has been implicated in a wide variety of degenerative processes, diseases and syndromes, including the following: mutagenesis, cell transformation and cancer; atherosclerosis, arteriosclerosis, heart attacks, ...
By the direct transformation of the peripheral ends of these cells; or by a secretion from them, a layer of uncalcified matrix (prodentin) is formed which caps the cusp or cusps, if there are more than one, of the papillæ.
First used for the transformation of prokaryotic cells by protein-free DNA or RNA from viruses. Also the process of genetic transformation in eukaryotic cells.
Related Terms:
Transformation ...
Darwin did think that the transformation would be slow, but he did not think that it would be "even". Darwin did not think that the transformation would involve large numbers, and certainly not the entire parent population.
They also discovered that protein-digesting enzymes (proteases) and RNA-digesting enzymes (RNAse) did not affect transformation, so the transforming substance was not a protein or RNA.
Desertification is transformation of marginal lands to desert conditions due to overgrazing and overfarming. This is most evident along the southern edge of the Sahara Desert in Africa.
Physics, which is the science that studies the transformations of the energy and their associations with matter.
Chemistry, which studies the transformations of the matter.
A gene that is capable of causing the transformation of normal cells into cancer cells. [Talking Glossary]
Organelle ...
metaplasia - the transformation of one differentiated cell type into another.
Also, the activation of an occult pathogen, leading to progressive infection and disease; in particular, the provoked transformation of a provirus into a virulent (cytocidal) virus. (Glossary of PM).
The change in free energy (.G) of a system undergoing transformation at constant pressure is equal to the change in enthalpy (.H) minus the product of the absolute temperature (T) and the change in entropy (.S).
processing and are transformed from an inactive to an active state. As outlined in Figure 1, lysosomes may then bud from the trans face of the Golgi apparatus, though they may also form via other mechanisms (such as the gradual transformation of ...
 See also: Trans, Organ, Human, DNA, Cells
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