Tumor Suppressor Genes
Some genes suppress tumor formation.
Their protein product inhibits mitosis.
When mutated, the mutant allele behaves as a recessive; that is, as long as the cell contains one normal allele, tumor suppression continues.
Tumor suppressor
Tumor suppressor genes inhibit progression in tumor development. They usually inhibit abnormal cell growth or promote apoptosis. Examples include p53 and Rb.
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Tumor
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tumor necrosis factor --> tumour necrosis factor
(Science: cytokine) Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or bacille Calmette-Guerin.
Tumor Suppressor Gene
A tumor suppressor gene directs the production of a protein that is part of the system that regulates cell division. The tumor suppressor protein plays a role in keeping cell division in check.
Tumor Suppressor
BRCA1 is believed to act as a tumor suppressor regulating cell growth and division. If suppressor genes are lost or damaged by mutation, uncontrolled cell growth can occur, resulting in cancer.
tumor
A mass that forms within otherwise normal tissue, caused by the uncontrolled growth of a transformed cell.
tumor suppressor gene ...
tumor suppressor genes Genes that normally keep cell division under control, preventing the cell from responding to internal and external commands to divide.
Tumor DNA. See T-DNA.
Tumor-inducing plasmid. See Ti plasmid.
Tumor virus. A virus capable of transforming a cell to a malignant phenotype. (See Virus.) ...
Tumor Biology
Cancer cells behave as independent cells, growing without control to form tumors. Tumors grow in a series of steps. The first step is hyperplasia, meaning that there are too many cells resulting from uncontrolled cell division.
tumor necrosis factor. A cytokine, the most important source of which is macrophages, that is a major mediator of inflammation.
tumor A spherical mass of cells in which cell divisions occur at random and often in an uncontrolled fashion.
Tumor suppressor: A gene that inhibits progression towards neoplastic transformation. The best-known examples of tumor suppressors are the proteins p53 and Rb.
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"The tumor-free time period, and is dated from the first, not the last, therapy session. Patients with tumors that recur within one month of treatment ending are considered to have had no remission.
neoplasm (tumor) - a synonym for cancerous tissue
serotonin - increase vascular permeability and smooth muscle contraction. Originates from platelets ...
swelling or tumor
Source: Noland, George B. 1983. General Biology, 11th Edition. St. Louis, MO. C. V. Mosby
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- The study of tumors.
Operon
- A group of functionally related structural genes mapping close to one another in the chromosome, transcribed into a single mRNA, and the adjacent transcriptional control sites (promoter and operator) ...
For detection of tumors, CT scanning with IV contrast is occasionally used but is less sensitive than magnetic resonance imaging (MRI).
A malignant tumor derived from epithelial tissue, which forms the skin and outer cell layers of internal organs. Catalyst.
Oncogenes -- genes involved in cell cycle control (growth factors, growth factor regulator genes, etc), a mutation can lead to tumor growth.
T cells killing a tumor cell
(1257 kb)
Human Immunodeficiency Virus (HIV) specifically attacks Helper T cells.
Haas, Burnham and Mills 1997 used a multiobjective genetic algorithm to optimize the beam shape, orientation and intensity of X-ray emitters used in targeted radiotherapy to destroy cancerous tumors while sparing healthy tissue.
The only plasmid that plant cells take up is the Ti (tumor-inducing) plasmid from the bacterium Agrobacterium. The plasmid transferred by this bacterium causes plants to form a gall.
The chief agent in the restoration of the axillary artery below the tumor was the subscapular artery, which communicated most freely with the internal mammary, ...
Agrobacterium tumefaciens: A gram-negative, rod-shaped flagellated bacterium responsible for crown gall tumor in plants.
metastasis The process in which cancer cells break away from the original tumor mass and establish new tumor sites elsewhere in the body.
methanogens A group of archaebacteria that produce methane as a by product of their metabolism.
Hematoma local swelling‚ tumor‚ or bruise filled with blood
(hemo = blood; -oma = tumor)
Heme Group a porphyrin ring with iron in the center
(heme‚ hemo = blood) ...
This releases a host of inflammatory materials - leukotrienes, tumor necrosis factor, interleukin-4 and other cytokines that turn on other inflammatory cells.
Repeated copying of a piece of DNA; a characteristic of tumor cells.
See also: gene, oncogene
Gene chip technology ...
Agrobacterium tumefaciens: A soil bacterium that causes a cancer-like plant disease (crown gall) in dicotyledenous plants (all agricultural crops except cereals). It contains the Ti plasmid. The tumor induction ability of the bacterium ...
It arises from a single cell that has lost the control over cell division and keeps dividing until it forms a tumor or a cancer.
Hybridoma cell A cell, resulting from the fusion of an antibody-producing cell and a tumor cell, that produces a single antibody and has an unlimited capacity for proliferation.
solution is sprayed as a stream of fine droplets past a laser and computer sensor, a machine can identify whether the cells in the droplets have been "tagged" by the antibodies. This has found extensive use in cancer research, for "tagging" tumor ...
 See also: Trans, Cancer, Cells, Human, Cell
  
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