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Uniparental disomy

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Uniparental disomy The inheritance of both copies of a single chromosome from one parent (and neither copy from the other).

 


Genomic imprinting and uniparental disomy, however, may affect inheritance patterns.

Non-traditional inheritance: mosaicism, microdeletion syndromes, uniparental disomy, genomic imprinting, trinucleotide repeats, mitochondrial disorders
The events in sexual development and some genetic abnormalities ...

Background materials for teachers discuss a wider range of phenomena that require nontraditional views of inheritance, including RNA editing, genomic imprinting, transposable elements, and uniparental disomy.

Apart from being an important cause of uniparental disomy, it may cause trisomy 21 (Down's syndrome) in the offspring.

See also: Human, Organ, Genetics, DNA, Blood