Zinc finger
A DNA binding protein structural motif. Present in many transcription factors (e.g., Sp1, Gal4). The "finger" is formed by 2-4 Cysteine residues and one zinc ion.
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Zinc finger: A protein structural motif common in DNA binding proteins. Four Cys residues are found for each "finger" and one finger can bind a molecule of zinc. A typical configuration is: CysXxxXxxCys--(intervening 12 or so aa's)--CysXxxXxxCys.
(2) Zinc finger DNA-binding domains
Greig cephalopolysyndactyly syndrome Â- Pallister-Hall syndrome Â- X-linked adrenal hypoplasia congenita Â- Autoimmune polyendocrine syndrome type 1
(3) Helix-turn-helix domains ...
Genetic and physical mapping studies indicate that hundreds, if not thousands, of zinc finger (ZNF)-containing genes populate the human genome, and that many of these genes, including those with Kruppel-associated box (KRAB) motifs, ...
where CCCC is the DNA-binding domain that contains zinc fingers, and EEEE the ligand-binding domain. The latter is also responsible for dimerization of most nuclearic receptors prior to DNA binding.
Zeatin Zebrafish (Danio rerio) Zellweger syndrome Zero population growth (ZPG) Zidovudine (AZT) Zincnutritional requirement Zinc finger[glucocorticoid receptor] [steroid hormone receptor superfamily] Zonules of human eye ZoologyStudy of animals.
DNA binding motif: Common sites on different proteins which facilitate their binding to DNA. Examples are leucine zipper and zinc finger proteins. Any such protein is called DNA-binding protein.
of the 5S rNA gene in xenopus by rNA polymerase III is dependent on a 40 kD protein TFIIIA that binds to a regulatory site in the centre of the gene and was the first protein found to exhibit the metal binding domains known as zinc fingers.
 See also: Protein, Gene, DNA, Trans, Sequence
  
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