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Alexander Disease

Disease Aldrich syndromeAlexia

Alexander disease is a rare disorder of the nervous system. It is considered one of the leukodystrophies, a group of disorders in which the primary abnormality is the inability to maintain myelin.

 


Alexander disease
Overview
Alexander disease (ALX) is a rare and often fatal nervous system disorder that primarily occurs in infants and children.

Alexander Disease
National Organization for Rare Disorders, Inc.
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Alexander Disease
By Dawn J. Cardeiro MS, CGCThe Gale Group Inc., Gale.. Gale Encyclopedia of Neurological Disorders, 2005more »
Definition ...

NINDS Alexander Disease Information Page
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What is Alexander disease?
Alexander disease is a rare disorder of the nervous system. It is one of a group of disorders, called leukodystrophies, that involve the destruction of myelin.

Alexander disease, ORI, HPB, CC, NIOSH, NEFLE, Dental Ethic, Dental Root Cyst, Dihydroxyacetone Phosphate, Ependymoma, Clear Cell, Epidemiologic Determinants, Folk Remedy, Geriatrics, Glycerophosphate, Choline, Hemoglobinuria, Interaction Map, ...

Alexander Disease
Alexander Graham Bell Association for Deaf and Hard of Hearing - Support Group
Alexander Graham Bell Association for Deaf and Hard of Hearing - Deaf / Hearing Impaired / Tinnitus / Meniere's - Support Group ...

Alexander disease
Alexander Leukodystrophy see Alexander disease
Alkaptonuria
ALL see Leukaemia and other Allied Blood disorders
Allergies
Alobar HPE see Holoprosencephaly
Alopecia
Alopecia Areata see Alopecia
Alopecia Totalis see Alopecia ...

Of the 3 subtypes of Alexander disease (infantile, juvenile, and adult), all three have been proven to be caused by mutations in GFAP. More than 20 GFAP mutations that cause Alexander disease have been identified.

Overuse of medicines may be the single biggest cause of nervous system problems in older adults.
Alexander Disease Causes, Symptoms And Treatment And Related Disorders ...

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GFAP (Glial Fibrillary Acidic Protein): The degenerative brain condition called Alexander disease is caused by mutation in GFAP (glial fibrillary acidic protein).

Pelizaeus-Merzbacher disease
Canavan disease
Childhood ataxia with central nervous system hypomyelination (CACH, also called vanishing white matter disease)
Alexander disease
Refsum disease
Cerebrotendinous xanthomatosis ...

metachromatic leukodystrophy, Krabbé disease, adrenoleukodystrophy, Pelizaeus-Merzbacher disease, Canavan disease, Childhood Ataxia with Central Nervous System Hypomyelination or CACH (also known as Vanishing White Matter Disease), Alexander disease, ...

See also: Dystrophy, Symptom, Leukodystrophy, Ataxia, Central nervous system

Disease Aldrich syndromeAlexia

 
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