Alanine transaminase (ALT) is an enzyme found in the highest amounts in the liver. Injury to the liver results in release of the substance into the blood.
Alternate Names : SGPT, Serum glutamate pyruvate transaminase, Alanine transaminase
ALT is present in many different kinds of tissue in the body. However, it is highly concentrated in the liver. Therefore, when the liver is injured, ALT is released into the bloodstream.
Review Date: 02/22/2009
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine.
An increase in ALT levels may be due to:
Death of liver tissue (liver necrosis)
Hepatitis (viral, autoimmune)
Infectious mononucleosis ...
An increase in ALT levels may be due to:
Cirrhosis (scarring of the liver)
Death of liver tissue (liver necrosis)
Lack of blood flow to the liver (liver ischemia)
Liver tumor or cancer
Medications that are toxic to the liver ...
Abbreviation: ' ALT '
Category: Common Medical Abbreviations
Meaning: Alanine Transaminase ...
See "Alanine aminotransferase"
1. In a trial, the alternative hypothesis might be that a treatment of unknown efficacy has more benefit than the standard treatment.
ALT (alanine aminotransferase): An enzyme normally present in liver and heart cells that is released into the bloodstream when the liver or heart is damaged from, for example, viral hepatitis or a heart attack).
ALT (alanine aminotransferase) definition - Health and Medical Information produced by doctors - MedicineNet.com
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ALT is an enzyme found mainly in liver cells, although smaller amounts are also in other organs of the body. When the liver becomes damaged, this enzyme leaks into the blood. A blood test can measure the level of ALT in the blood.
ALT (Alanine Aminotransferase)
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ALT is an enzyme that transfers an amino group from the amino acid alanine to a ketoacid acceptor (oxaloacetate). The enzyme was formerly called serum glutamic pyruvic transaminase (SGPT) after the products formed by this reaction.
ALT relatively lower than AST in alcoholism
Assess severity/chronicity ...
ALT: see alanine aminotransferase.
ALTERNATIVE THERAPY: any type of treatment that is not considered standard or conventional practice in a given culture.
ALT levels > 7 times the normal limits, and
IgM anti-HAV negative, and
IgM anti-HBc negative or HBsAg negative, and ...
ALT (SGPT) is, by contrast, normally found largely in the liver. This is not to say that it is exclusively located in liver, but that is where it is most concentrated. It is released into the bloodstream as the result of liver injury.
ALT is a form of outpatient adoptive immunotherapy utilizing autologous ex vivo activated T-cells accompanied by high dose cimetidine.
This section requires expansion.
ALT (SGPT) must be performed at baseline and monitored at monthly intervals during the first six months then, if stable, every 6 to 8 weeks thereafter.
During ALT surgery, a laser makes tiny, evenly spaced burns in the trabecular meshwork. The laser does not create new drainage holes, but rather stimulates the drain to function more efficiently.
Spinal tap (lumbar puncture)'insertion of a needle between the lumbar vertebrae in the back to remove spinal fluid for testing
Liver biopsy 'removal of a sample of liver tissue for testing ...
The liver enzymes (ALT and AST) may be elevated in chronic hepatitis C infection. ALT in HCV is not correlated with disease progression or underlying histology. Many patients with chronic hepatitis C have normal ALT levels.
Alanine aminotransferase (ALT). This enzyme, found in the liver, plays a role in metabolism, the process that converts food into energy. If the liver is injured, ALT is released into the bloodstream.
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Alanine transaminase (ALT). This is an enzyme that helps to process proteins. (An enzyme is a protein that helps to speed up chemical reactions. Various enzymes occur in the cells in the body.) Large amounts of ALT occur in liver cells.
Liver function tests (AST, ALT, alkaline phosphatase, bilirubin), which detect liver damage or disease.
Alanine aminotransferase (ALT), Dentins, Secondary, Diets, Chemically Defined, Diphyllobothriasis, Enterobacteria phage MS2, Erythroblastosis, Fetal, Habituation Spasm, Hemorrhagic Leukoencephalitides, Subacute, Hormone, Adrenocorticotropic, ...
Acute angle closure glaucoma, ALT, aqueous humor, argon laser trabeculoplasty, caffeine, canal of Schlemm, cataract, closed-angle glaucoma, congenital glaucoma, cornea, corticosteroid, diabetes, fluoroscein, glaucoma drainage device, ...
Elevation of liver enzymes (alkaline phosphatase, LDH, and ALT) suggests the presence of liver metastases. Elevated alkaline phosphatase and serum Ca may be the first evidence of bone metastases.
NASH is usually first suspected in a person who is found to have elevations in liver tests that are included in routine blood test panels, such as alanine aminotransferase (ALT) or aspartate aminotransferase (AST).
The procedure is called Argon Laser Trabeculoplasty or ALT. A newer type of laser trabeculoplasty exists that uses a "cold" (non-thermal) laser to stimulate drainage in the trabecular meshwork.
Normal Levels of AST and ALT
Elevated Levels of AST and ALT
Diseases That Cause Abnormal Aminotransferase Levels
Medications That Cause Abnormal Aminotransferase Levels
Less Common Causes of Abnormal Aminotransferase Levels ...
Tests: Blood tests of liver function show significantly elevated levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase, and bilirubin.
ALT - a raised level of this enzyme is the best indicator of hepatitis as this enzyme is mainly found in the liver.
ALP - the levels of this enzyme are usually raised when the bile ducts are blocked.
Argon Laser Trabeculoplasty (ALT)
Argon laser trabeculoplasty (ALT) is the most common type of laser surgery. It is usually used to treat open angle glaucoma. During this procedure, you will sit facing the laser machine.
Definition The alanine aminotransferase test, also known as ALT, is one of a group of tests known as liver function tests (or LFTs) and is used to monitor damage to the liver.
Baseline laboratory studies include bilirubin, AST, ALT, and prothrombin time (with INR). Studies are repeated at least daily.
Argon laser trabeculoplasty (ALT) may be the initial treatment for patients who do not respond to or who cannot tolerate drug therapy.
alanine transaminase (ALT) test
This test measures the level of alanine aminotransferase (an enzyme found predominantly in the liver) that is released into the bloodstream after acute liver cell damage.
In chronic hepatitis, the liver function tests show higher levels of the transaminases (ALT and AST) than the other liver enzymes. Hepatitis B and C tests, autoantibodies, copper and caeruloplasmin levels, and other tests are also necessary.
It is mentioned in the prescribing information that Arimidex can cause elevations in ALT, AST and bilirubin ...
Should I Be Drinking Artificial Sugars Such As Splenda?
passed in the breast milk to infants. Concerning...
This includes measuring the aminotransferases enzymes (AST and ALT levels) ...
Liver enzymes: Another blood test may be performed to check for elevated levels of liver enzymes, such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST). These enzymes leak into the bloodstream when liver cells are injured.
At the onset of treatment 7 of the 8 patients also had elevated liver enzyme levels - SGOT (AST) and SGPT (ALT). Following ozone therapy these measures fell into the normal range.
Alanine Aminotransferase (ALT)
A liver enzyme that plays a role in protein metabolism. Abnormally high blood levels of ALT are a sign of liver inflammation or damage from infection or drugs. A normal level is below approximately 50 IU/L.
Elevated alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are nonspecific indicators of hepatocellular damage and do not distinguish viral from drug-induced hepatitis.
Glaucoma Laser Treatment: ALT
Glaucoma Laser Treatment: CPC
LASIK with the VISX CustomVue System
Photodynamic Therapy for Wet ARMD
Refractive Lens Exchange
Sutureless Corneal Transplant (DSAEK)
Liver test abnormally high-elevated AST, ALT, bilirubin
Kidney tests may be high-elevated BUN, creatinine
Tests may be done to rule out the presence of other drugs.
Alanine Aminotranferase (ALT)
Alkaline Phosphatase (ALP, Alk Phos)
Gamma Glutamyl Transferase (Gamma GT, GGT)
Total Protein (TP) ...
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It is important to monitor alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels at 1mo and then every 3mo after the initiation of antiretroviral therapy ...
SGOT (serum glutamic oxaloacetic transaminase), also called AST (aspartate aminotransferase)
SGPT (serum glutamic pyruvic transaminase), also called ALT (alanine aminotransferase)
LDH (lactate dehydrogenase) ...
Dubin-Johnson syndrome is an autosomal recessive disorder that causes an increase of conjugated bilirubin without elevation of liver enzymes (ALT, AST). This condition is associated with a defect in the ability of hepatocytes...
Full article ...
SGPT: (Serum Glutamic Pyruvate Transaminase.) Also known as ALT (alanine aminotransaminase), a liver enzyme that plays a role in protein metabolism like SGOT (see). An elevated serum level of SGPT is a sign of liver damage from disease or drugs. ...
ESR (sedimentation rate), a measure of inflammation, will be higher than normal.
Ferritin level will be very high.
Fibrinogen level will be high.
Liver function tests will show high levels of AST and ALT.
SGOT is sometimes called aspartate transaminase (AST), and SGPT is sometimes called alanine aminotransferase (ALT). Studies may also be performed looking for deposits within the cells of the liver called inclusions.
BUN (blood urea nitrogen) and creatinine: Evaluates your kidney function.
Liver function tests: Includes ALP (alkaline phosphatase), ALT (alanine aminotransferase), aspartate aminotransferase (AST) and bilirubin, among others.
See also: Symptom, AST, Hepatitis, Liver disease, Jaundice