Alveolar rhabdomyosarcoma

Alveolar rhabdomyosarcoma is a type of rhabdomyosarcoma characterized by its appearance, which is similar to the alveoli of the lungs.
It can be associated with a fusion protein between PAX3 and FKHR (now known as FOXO1).[1][2] ...

Alternate Names : Soft tissue sarcoma, Alveolar rhabdomyosarcoma, Embryonal rhabdomyosarcoma, Sarcoma botryoides
Definition ...

Alveolar rhabdomyosarcoma. This is a more aggressive type of rhabdomyosarcoma, found most often in the arms, legs, or trunk of the body.

Alveolar Rhabdomyosarcoma
Approximately 20% of children with rhabdomyosarcoma have the alveolar subtype.

Soft tissue sarcoma; Alveolar rhabdomyosarcoma; Embryonal rhabdomyosarcoma; Sarcoma botryoides
Causes
The cause of rhabdomyosarcoma is unknown. It is a rare tumor with only several hundred new cases per year throughout the United States.

In alveolar rhabdomyosarcoma, a rearrangement in the chromosome material between chromosomes #2 and #13 is usually present. This rearrangement changes the position and function of genes, causing a fusion of genes referred to as a "fusion transcript.

In general, embryonal rhabdomyosarcoma tends to be a localized cancer that responds well to treatment and rarely spreads (metastasizes) away from the site where it started, while alveolar rhabdomyosarcoma tends to be aggressive and hard to treat.

Alveolar rhabdomyosarcoma (See Rhabdomyosarcoma)
Alveolar soft part sarcoma (See Soft Tissue Sarcoma)
Alzheimer's dementia (See Alzheimer's Disease)
Alzheimer's Disease
AMD (See Macular degeneration)
Ameloblastoma
Ampullary Cancer
Amyloidosis ...

See also: Rhabdomyosarcoma, Sarcoma, Cancer, Liposarcoma, Synovial sarcoma