Aplastic crisis

Sickle Cell Disease: Aplastic Crisis
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Primary complications include increasing severity of anemia during crisis times (hemolytic crisis and aplastic crisis) and pigment gallstones with or without inflammation of the gallbladder (cholecystitis).

Acute chest crisis, Anemia, aplastic crisis, autosomal recessive, beta thalassemia, genetic counseling, genetic testing, genetic screening, HBB gene, HbC, HbE, HbS disease, HbSBetaThal disease, HbSC disease, HbSE disease, hemoglobin C, hemoglobin E, ...

Gallstones
Much lower red blood cell production (aplastic crisis) caused by a viral infection, which can make anemia worse
When to Contact a Medical Professional ...

Hemolytic crisis occurs when damaged red blood cells break down
Splenic sequestration crisis is when the spleen enlarges and traps the blood cells
Aplastic crisis results when an infection causes the bone marrow to stop producing red ...

Definitions:
1. a human parvovirus associated with arthritis and arthralgia and a number of specific clinical entities, including erythema infectiosum and aplastic crisis in the presence of hemolytic anemia.

In people with certain red blood cell abnormalities, such as sickle cell disease, this infection can cause an aplastic crisis.

The bone marrow has to work extra hard to make more red cells. So, if in the course of an ordinary viral illness, the bone marrow stops making red cells, the anemia can quickly become profound. This is termed an aplastic crisis.

However, another member of the Parvoviridae family, a parvovirus termed B19, causes erythema infectiosum (fifth disease or "slapped cheek" syndrome), hydrops fetalis (severe anemia in pregnant women), and aplastic crisis (cessation of red blood cell ...

See also: Anemia, Symptom, Fever, Viral, Rash