Attenuated FAP

Attenuated FAP
Overview
An inherited condition where polyps develop in the lining of the gastrointestinal tract. The polyps are initially benign but may become malignant if untreated.

Attenuated FAP
A type of inherited colorectal cancer in which individuals usually have fewer polyps and a later age of onset than in classic familial adenomatous polyposis (FAP).
Familial adenomatous polyposis, Polyp ...

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A rare form of FAP exists, known as attenuated FAP. In this condition, the mutation occurs at the extreme end of the APC gene, which, presumably, causes only a relatively minor defect in the function of the APC protein.

There are three subtypes of classic FAP called attenuated FAP, Gardner syndrome, and Turcot syndrome. This section addresses classic FAP.
What causes FAP?

Gardner Syndrome
Turcot Syndrome
familial adenomatous polyposis
attenuated FAP ...

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See also: Cancer, Rectal cancer, Colorectal Cancer, Polyposis, Adenoma