Castleman Disease

Castleman Disease
Castleman disease (CD) is a disease of lymph nodes and related tissues. CD is also known as giant lymph node hyperplasia and angiofollicular lymph node hyperplasia.

Castleman disease can occur in a localized or a more widespread form. Treatment and outlook depend on which type of Castleman disease you have.
Symptoms
References ...

Castleman disease: A disorder of lymphoid tissue (lymphadenopathy) with massive overgrowth (hyperplasia) of lymph nodes ("swollen glands"), most commonly affecting the nodes between the lungs (in the mediastinum).

Goedert JJ: Multicentric Castleman disease: viral and cellular targets for intervention. Blood 102 (8): 2710-11, 2003.
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Marcelin AG, Aaron L, Mateus C, et al.: Rituximab therapy for HIV-associated Castleman disease. Blood 102 (8): 2786-8, 2003.
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Castleman disease (KA-sel-man dih-ZEEZ) A rare disorder in which growths that are benign (not cancer) develop in lymph node tissue.
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Human herpesvirus 8: Kaposi's sarcoma, primary effusion lymphomas, and multicentric Castleman disease (a lymphoproliferative disorder)
Diagnosis ...

See also: Cancer, Lymphoma, Infections, Fever, Herpes