Chimerism is an extremely rare disorder that mixes the chromosomal population in a single organism. In these cases, chimerism may manifest as the presence of two sets of DNA, or organs that do not match the DNA of the rest of the organism.
Induction of chimerism (coexistence of donor and recipient immune cells in which graft tissue is recognized as self) using nonmyeloablative pretransplantation treatment (eg, with cyclophosphamide Some Trade Names
CYTOXAN
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However, if microchimerism plays a role, it most likely does so only in a subset of patients.
Triggering the Immune Response ...
: Allogeneic transplantation for pediatric acute lymphoblastic leukemia: the emerging role of peritransplantation minimal residual disease/chimerism monitoring and novel chemotherapeutic, molecular, and immune approaches aimed at preventing relapse.
 See also: Cancer, Lymphoma, Blood Transfusion, Fusion, Graft-versus-host disease
  
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