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Chondrocalcinosis

Chondrocalcinosis, Familial Articular Causes, Symptoms and Treatment and Related Disorders ...

chondrocalcinosis
kndrkls nss noun a condition in which deposits of calcium phosphate are found in articular cartilage
chondrocyte ...

Chondrocalcinosis: Calcium in cartilage, usually in a joint, as in osteoarthritis.
Chondroitin sulfate: A glycosaminoglycan (formerly called a mucopolysaccharide) found in cartilage, bone, blood vessels and connective tissues.

Chondrocalcinosis
Chondromalacia patella
Chondrosarcoma
Chordee
Chorioretinitis
Chromosome 22q11 deletion syndrome
Chronic atrophic pyelonephritis - adult
Chronic atrophic pyelonephritis - child
Chronic bronchitis ...

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Familial Articular Chondrocalcinosis ... joint stiffness, joint damage, joint pain, joint swelling
Familial Cold Autoinflammatory Syndrome (FCAS) ... joint pain, joint swelling, stiff joints
Familial dilated cardiomyopathy ... swollen ankles ...

Mutations in ANKH cause chondrocalcinosis. Am J Hum Genet. 2002 Oct;71(4):933-40. Epub 2002 Sep 20. PubMed citation ...

Calcium pyrophosphate crystal deposition disease, pseudogout, and articular chondrocalcinosis. In: Arthritis and Allied Conditions, 15th ed, Koopman, WJ, Moreland, LW (Eds), Lippincott, Williams and Wilkins, Philadelphia 2005. p.2373.

The incidence of radiologic (usually asymptomatic) chondrocalcinosis in patients aged 70 is about 3%, reaching nearly 50% in patients aged 90. Asymptomatic chondrocalcinosis is common in the knee, hip, anulus fibrosus, and symphysis pubis.

In gout, the crystal is uric acid.
In pseudogout/chondrocalcinosis/calcium pyrophosphate deposition disease, the crystal is calcium pyrophosphate.
Diabetic arthropathy (M14.2, E10-E14) is caused by diabetes.

However, in this condition, also called chondrocalcinosis, deposits are made up of calcium phosphate crystals, not uric acid. Therefore, pseudogout is treated somewhat differently and is not reviewed in this booklet.

Conditions that precipitate secondary osteoarthritis (e.g., hemochromatosis, gout, chondrocalcinosis, intra-articular fracture)
Obesity
Factors Influencing Duration ...

(Calcium Pyrophosphate Deposition Disease; Calcium Pyrophosphate Dihydrate Crystal Deposition Disease; Chondrocalcinosis)
Pronounced: SOO-doh-gowt
Diane A. Safer, PhD ...

Pseudogout is suggested when abnormal calcifications are seen in the cartilage of joints on x-ray testing. These calcifications are referred to as chondrocalcinosis.

Another condition, pseudogout (chondrocalcinosis), which mainly occurs in older adults, can cause severe inflammation and intermittent attacks of pain and swelling in large joints, especially the knees.

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Topic: Disease