Costello Syndrome

Costello Syndrome Causes, Symptoms and Treatment and Related Disorders ...

What is Costello syndrome?
Costello syndrome is a disorder that affects many parts of the body.

Costello syndrome.
Noonan syndrome.
High birth weight and larger than expected size at birth are linked with an increased risk of embryonal rhabdomyosarcoma.

Costello syndrome
Cardio-facio-cutaneous syndrome
A few cases of rhabdomyosarcoma have been associated with some congenital (present at birth) anomalies (abnormalities).

RAS: HRAS (Costello syndrome) Â- KRAS (Noonan syndrome 3, KRAS Cardiofaciocutaneous syndrome)
RAB: RAB7 (Charcot-Marie-Tooth disease) Â- RAB23 (Carpenter syndrome) Â- RAB27 (Griscelli syndrome type 2)
RHO: RAC2 (Neutrophil immunodeficiency syndrome) ...

International Costello Syndrome Support Group - Support Group
International Costello Syndrome Support Group - Costello Syndrome - Support Group
International Doctors in Alcoholics Anonymous - Support Group ...

: HRAS mutation analysis in Costello syndrome: genotype and phenotype correlation. Am J Med Genet A 140 (1): 1-7, 2006.
Aoki Y, Niihori T, Kawame H, et al.: Germline mutations in HRAS proto-oncogene cause Costello syndrome.

Costello syndrome
Cot Death
Cowden disease
Cowden syndrome see Cowden disease
Coxa Plana see Perthes disease
CPS Deficiency see Urea Cycle Disorders
CPT I see Fatty Acid Oxidation Disorders
CPT II see Fatty Acid Oxidation Disorders ...

Costello syndrome
Ectodermal dysplasia anhidrotic
Fryns-Smeets-Thiry syndrome
Hyperphalangism - dysmorphy - bronchomalacia
Hypertrichotic osteochondrodysplasia
Hypohidrotic Ectodermal Dysplasia
Hypomelanosis of Ito
Marshall syndrome ...

of BWS, several other syndromes should also be considered (differential diagnosis). These include, but are not limited to, infant of a diabetic mother, Simpson-Golabi-Behmel syndrome, Perlman syndrome, Sotos syndrome, and Costello ...

Costello Syndrome
Costes Syndrome
Costochondral Junction Syndrome
costovertebral segmentation anomalies
Costovertebral segmentation defect with mesomelia (formerly)
Cot Death
Cottonmouth (Water Moccasin)
Cough Symptoms in Children ...

Costello syndrome ... low-set ears
Coxoauricular syndrome ... small ears, deafness
Crack addiction ... auditory hallucinations
Cradle Cap ... ear rash
Crandall syndrome ... deafness
Cranio-facio-cardio-skeletal dysplasia ... low set ears ...

See also: Symptom, Cancer, Surgery, Aging, Rhabdomyosarcoma