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Glucocorticoid deficiency

Disease Glucagonoma syndromeGlucose tolerance test

Chronic fatigue (glucocorticoid deficiency?)
Mineralocorticoid excess
Hypertension ...

 


Stewart PM (2008). Glucocorticoid deficiency section of The adrenal cortex. In HM Kronenberg et al., eds., Williams Textbook of Endocrinology, 11th ed., pp. 445-485. Philadelphia: Saunders.
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Secondary adrenal hypofunction that results in glucocorticoid deficiency can stem from hypopituitarism (causing decreased corticotropin secretion), ...

Zuckerman-Levin N, Tiosano D, Eisenhofer G, et al. The importance of adrenocortical glucocorticoids for adrenomedullary and physiological response to stress: a study in isolated glucocorticoid deficiency. J Clin Endocrinol Metab. 2001;86(12):5920-4.

A serum cortisol level < 13 ug/dL (in combination with an increased ACTH level) suggests glucocorticoid deficiency due to primary adrenal insufficiency. CT, MRI, or ultrasonography of the adrenal glands is done.

Familial glucocorticoid deficiency (ACTH receptor mutation).
Haemochromatosis.
Haemorrhage - usually in patients receiving anticoagulant drugs or in whom septicaemia ('blood poisoning') is present.
HIV-related adrenal inflammation.

Philadelphia: Lippincott Williams and Wilkins.
Stewart PM (2008). Glucocorticoid deficiency section of The adrenal cortex. In HM Kronenberg et al., eds., Williams Textbook of Endocrinology, 11th ed., pp. 445-485. Philadelphia: Saunders.

See also: Deficiency, Infections, Stress, Surgery, Symptom

Disease Glucagonoma syndromeGlucose tolerance test

 
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