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Hemolytic crisis

Disease Hemolytic anemiaHemolytic Disease of Newborn

Hemolytic crisis
Definition
Hemolytic crisis occurs from the rapid destruction of large numbers of red blood cells (hemolysis). The destruction occurs much faster than the body can produce new red blood cells.

 


Hemolytic crisis occurs from the rapid destruction of large numbers of red blood cells (hemolysis). The destruction occurs much faster than the body can compensate by producing more red blood cells.
Alternative Names
Hemolysis - acute ...

Hemolytic crisis occurs when damaged red blood cells break down
Splenic sequestration crisis is when the spleen enlarges and traps the blood cells ...

Hemolytic crisis is a group of symptoms that occur when many red blood cells suddenly die all at once. The symptoms that result include:
weakness
pain in the abdomen or back
jaundice
dark urine
fever and chills
severe fatigue ...

Hemolysis - acute (Hemolytic crisis)
Hemolytic anemia
Hemolytic anemia caused by chemicals and toxins
Hemolytic anemia due to G6PD deficiency (Glucose-6-phosphate dehydrogenase deficiency)
Hemolytic crisis ...

Primary complications include increasing severity of anemia during crisis times (hemolytic crisis and aplastic crisis) and pigment gallstones with or without inflammation of the gallbladder (cholecystitis).

Sudden attacks of G6PD deficiency, or a hemolytic crisis, can be caused by:
any serious illness
fava beans, in the more rare forms of G6PD deficiency
sulfa medications, such as sulfamethoxazole, an antibiotic ...

Fever, viral and bacterial infections, and diabetic acidosis can also precipitate a hemolytic crisis (when the red blood cells break up), resulting in anemia and jaundice. Large IV doses of vitamin C should also be avoided in these people.

See also: Anemia, Infections, Deficiency, Fever, Antibiotic

Disease Hemolytic anemiaHemolytic Disease of Newborn

 
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