Hereditary Spastic Paraplegia

Hereditary spastic paraplegia, autosomal dominant: A degenerative disorder of nerves with progressive spasticity of the legs. Abbreviated as AD-HSP.

NINDS Hereditary Spastic Paraplegia Information Page
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Hereditary spastic paraplegia (HSP) is a group of inherited neurological disorders characterized by progressive weakness (paraplegia) and increased muscle tone and stiffness (spasticity) of leg muscles.

Hereditary spastic paraplegia (HSP), also called familial spastic paraparesis, is characterized by progressive spasticity in the lower extremities that can become severe and incapacitating.

Hereditary spastic paraplegia (HSP): Hereditary spastic paraplegia or HSP is a group of genetic disorders that affects the spinal cord and results in weakness and stiffness of the legs.

Like all hereditary spastic paraplegias, spastic paraplegia type 11 involves spasticity of the leg muscles and muscle weakness.

Autosomal dominant hereditary spastic paraplegia, Directory, Dysfunction, Multiple Peroxisomal, FMRFamide, Genes, Lac, Gonadotropin Resistant Ovary Syndrome, Heterologous Antigens, Idioventricular Rhythms, Accelerated, Infection, Phasmidia, ...

X linked Recessive Hereditary Spastic Paraplegia
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Hereditary spastic paraplegia 3A associated with axonal neuropathy. Arch Neurol. 2007 May;64(5):706-13. PubMed citation ...

Hereditary Spastic Paraplegia ... speaking difficulty
HERNS syndrome ... dysarthria
Histidinemia ... speech retardation
Hoarseness ... partial loss of voice, total loss of voice, hoarseness
Homocystinuria ... delayed speech development ...

Genetic disorder (hereditary spastic paraplegia)
Congenital (present at birth)
Infection
Autoimmune diseases
Tumor (either within the spinal cord or compressing the spinal cord)
Syrinx (a spinal chord disorder) ...

Autonepiophilia Autonomic failure Autonomic nervous system Autonomy, patient Autophilia Autophobia Autoplastic Autopsy Autoradiography Autosexual Autosomal Autosomal chromosome Autosomal dominant Autosomal dominant hereditary spastic paraplegia ...

See also: Spastic paraplegia, Paraplegia, Plegia, Symptom, Stroke