What is Hirschsprung disease (HD)?
Hirschsprung* disease (HD) is a disease of the large intestine that causes severe constipation or intestinal obstruction. Constipation means stool moves through the intestines slower than usual.
Hirschsprung disease is a blockage in the large intestine. It is caused by an lack of nerve cells in a portion of the intestine. A person is born with this condition.
What is going on in the body?
Hirschsprung disease The congenital absence of autonomic ganglia (nerves controlling involuntary and reflexive movement) in the muscles of the colon.
Hirschsprung disease (HSCR)
HSCR (OMIM), a disorder of the enteric plexus of the colon that typically results in enlargement of the bowel and constipation or obstipation in neonates, is observed in a small number of individuals with MEN 2A, FMTC, ...
Hirschsprung disease: A congenital abnormality (birth defect) of the bowel in which there is absence of the ganglia (nerves) in the wall of the bowel. Nerves are missing starting at the anus and extending a variable distance up the bowel.
Hirschsprung disease is an important condition. It is the commonest cause of lower intestinal blockage (obstruction) in the newborn period and later in infancy and childhood, Hirschsprung disease is a cause of chronic constipation.
Hirschsprung Disease-Mental Retardation Syndrome
Microcephaly, Mental Retardation, and Distinct Facial Features, with or without Hirschsprung disease
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Hirschsprung Disease Index
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Hirschsprung disease (a condition present at birth that causes blockage of the large intestine due to lack of muscle contractions) is also associated with medullary thyroid carcinoma.
Hirschsprung disease has been associated in a small percentage of cases with the development of neuroendocrine tumors such as medullary thyroid carcinoma.
eMedicine - Hirschsprung Disease : Article by Steven L Lee, MD
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Howstuffworks "Rectocele: A Profile of a Condition Caused by Childbirth" ...
Hirschsprung Disease ... Stool impaction, Constipation, Constipation from birth
Hirschsprung disease -- deafness -- polydactyly ... constipation
Hirschsprung disease -- polydactyly -- heart disease ... constipation ...
True constipation in infants and children that has been present since birth may be Hirschsprung disease. This is a congenital condition that is uncommon.
cystine transport Disease, degenerative joint Disease, exaggerated startle Disease, Fahr Disease, Forestier Disease, Graves Disease, gum Disease, hand-foot-and-mouth Disease, Heberden Disease, hemolytic of the newborn Disease, Hirschsprung Disease, ...
Hirschsprung disease. In FD Burg et al., eds., Current Pediatric Therapy, 18th ed., pp. 529-532. Philadelphia: Saunders Elsevier.
Milla PJ (2006). Hirschsprung's disease. In MM Wolfe et al., eds., Therapy of Digestive Disorders, 2nd ed., pp.
Neuroblastoma can be seen with Hirschsprung disease (a disease of the large intestine), congenital central hypoventilation syndrome (CCHS; a condition that affects a person's nighttime breathing function), pheochromocytoma, ...
Risk factors that can make a person more likely to have sigmoid volvulus are Hirschsprung disease, intestinal pseudo-obstructions, and megacolon (an enlarged colon). Adults, children, and infants can all have sigmoid volvulus.
The most common medical problems that cause constipation include Hirschsprung disease (an abnormality of nerves in the colon), abnormal development of the anus, problems absorbing nutrients, spinal cord abnormalities, and certain medicines.
Wyllie R. Motility Disorders and Hirschsprung Disease. In: Kliegman RM, Jenson HP, Stanton BF, eds. Kliegman: Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 329.
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Brain Anomalies-retardation Of Mentality And Growth-ectodermal Hypoplasia-Hirschsprung Disease-ear Deformity And Deafness-eye Hypoplasia-cleft Palate-cryptorchidism-kidney Dysplasia/hypoplasia [syndrome]
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Wyllie R (2007). Motility disorders and Hirschsprung disease. In RM Kliegman et al., eds., Nelson Textbook of Pediatrics, 18th ed., pp. 1564-1568. Philadelphia: Saunders Elsevier.
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A rare disorder characterized by Hirschsprung disease (an intestinal disorder), nail abnormalities and facial anomalies.
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Albinism, cochlear implants, congenital hearing loss, gray hair, hearing loss, Hirschsprung disease, Hirschsprung's disease, inherited disorders, Klein-Waardenburg syndrome, Waardenburg-Shah syndrome, white forelock.
Certain types, however, may have some limb and digit malformations with fused fingers and mild underdevelopment of arms and legs. Another type (4) is associated with an abnormality in the colon called Hirschsprung disease which results in dilation ...
 See also: Symptom, Kidney, Constipation, Surgery, Diarrhea
  
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