The cause of TSP was obscure until the mid-1980s, when an important association was established between the human retrovirus - human T-cell lymphotrophic virus type 1 (also known as HTLV-1) - and TSP.
A human retrovirus of the lentivirus family, notable for long duration of asymptomatic infection, often followed by progressive deterioration of cell mediated immune function, and eventual opportunistic infection and neoplasm.
XMRV is a newly identified human retrovirus that is similar to a group of mouse retroviruses (called murine leukemia viruses, or MLVs) scientists have known about for years. XMRV refers to xenotropic murine leukemia virus-related virus.
?25% of breast cancer contained a new human retrovirus called XMRV. 178 cases of breast cancer were examined for the presence of XMRV. Approximately 25% of breast cancers contained either XMRV proviral DNA sequences or XMRV proteins.
Experiments on mice and other mammals have demonstrated the relevance of retroviruses in leukemia, and human retroviruses have also been identified.
AIDS results from an infection with one of two of the Human Immunodeficiency Viruses (HIV), a human retrovirus that primarily infects and destroys certain types of white blood cells (helper-inducer subset of T-lymphocyte white cells), ...
This work led to the identification of a novel human retrovirus, designated xenotropic murine leukemia virus-related virus.
See also: Symptom, Immune System, Cancer, HIV, Viral
 
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