Hypereosinophilic syndrome

What is Hypereosinophilic Syndrome?
Hypereosinophilic Syndrome (HES) refers to a group of diseases that are characterised by an excessive amount of eosinophils (a normal cellular component from the myeloid series of the blood that stains red with ...

Hypereosinophilic syndrome (HES)
A group of disorders in which the bone marrow produces too many eosinophils (one type of white blood cell). The eosinophils gradually build up in body tissues and damage body organs.
Hyperplasia ...

Hypereosinophilic Syndrome and Clonal…
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Hypereosinophilic syndrome
Hypereosinophilic syndrome is a condition where there is no apparent cause for eosinophilia.

Hypereosinophilic Syndrome: A condition in which the number of eosinophils in the blood is markedly and persistently elevated with no apparent cause, such as an allergic disease or a parasitic infection.

Acute hypereosinophilic syndrome (a rare but sometimes fatal leukemia-like condition)
An allergic reaction (can also reveal how severe the reaction is)
Early stages of Cushing's disease
Infection by a parasite
How is the Test Performed?

Hypereosinophilic Syndrome (5 images)
Hyperergic Reaction after Vaccination (1 images)
Hyperhidrosis (0 images)
Hyper-IgE Syndrome (0 images)
Hyperkeratotic Fissured Hand and Foot Eczema (7 images)
Hypersensitivity Angiitis (Zeek) (0 images) ...

Weller PF, Bubley GJ: The idiopathic hypereosinophilic syndrome. Blood 83 (10): 2759-79, 1994.
Basara N, Markova J, Schmetzer B, et al.: Chronic eosinophilic leukemia: successful treatment with an unrelated bone marrow transplantation.

Idiopathic hypereosinophilic syndrome ... joint pain
Idiopathic pulmonary hypertension ... swollen ankles
IgA nephropathy ... Arthritis
Iliotibial Band Syndrome ...

In many patients with hypereosinophilic syndrome, the leukemic cells have a specific genetic abnormality or mutation that produces an abnormal protein (known as FIP1-like-1/platelet-derived growth factor alpha) that stimulates the cells to grow.

It can arise de novo or may develop in patients having the chronic form of a hypereosinophilic syndrome. Patients with acute eosinophilic leukemia have a propensity for developing bronchospasm and heart failure from endomyocardial fibrosis.

Allergic Bronchopulmonary Aspergillosis
Acute and Chronic Eosinophilic Pneumonia
Churg-Strauss Syndrome
Idiopathic Hypereosinophilic Syndrome ...

Lung diseases, such as Loffler's syndrome
Vasculitis (eg, Churg-Strauss syndrome)
Some tumors
Liver cirrhosis
Some antibody deficiencies
Rare skin disease, such as dermatitis herpetiformis
Unknown causes, labeled hypereosinophilic syndrome ...

considered in the differential diagnosis, such as rheumatic fever, arthritis, angioedema, botulism, collagen vascular disease, dermatomyositis, encephalitis, eosinophilia-myalgia syndrome, gastroenteritis, idiopathic hypereosinophilic syndrome, ...

See also: Cancer, Infections, Lymphoma, Fibrosis, Fever