IgA deficiency is inherited, which means it is passed down through families. It may be inherited as an autosomal dominant or autosomal recessive trait. It is found in approximately 1 in 700 individuals of European origin.
Most people with IgA deficiency don't have recurrent infections. However, some people who have IgA deficiency experience recurrent respiratory tract infections, asthma, sinus infections, allergies and diarrhea.
Why choose Mayo Clinic ...
IgA Deficiency
Between 2 and 3 percent of celiac patients have selective IgA deficiency—a rate about 10 times higher than in the general population.
IgA deficiency
Definition of Selective deficiency of IgA:
Selective deficiency of IgA is the most common immune deficiency disorder. Persons with this disorder have low or absent blood levels of a special protein called immunoglobulin A.
IgA deficiency: What is it?
© 1998-2006 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.
Selective IgA Deficiency ... recurring lung infections
Septo-Optic Dysplasia ... apnea
Severe infantile axonal neuropathy ... respiratory failure
Severe, refractory asthma ... severe breathing difficulty, asphyxia, asphyxia
Shy-Drager Syndrome ...
Secretory IgA Deficiency
Anti-Epstein-Barr Virus Nuclear Antigen (EBNA) Antibody Deficiency
Adenosine Deaminase Deficiency, Severe Combined Immunodeficiency with
Dysgammaglobulinemia, Janeway
Immunodeficiency Common, Variable, Unclassifiable ...
Data Quality, Diphosphokinases, Nucleoside, Disadine, Endonuclease, Neurospora, Financial Gifts, FL 1039, Formations, Rosette, Genes, nf 1, Health Centers, Rural, Hematopoietin-2, Holocaust, IgA Deficiency, Ion-Selective Electrodes, Isomerase, ...
The most common immunodeficiency disorder is IgA deficiency, in which the body doesn't produce enough of the antibody IgA, an immunoglobulin found primarily in the saliva and other body fluids that help guard the entrances to the body.
Common variable immunodeficiency or IgA deficiency
Pneumocystis infections, cryptosporidiosis, or toxoplasmosis
T-cell disorders or occasionally Ig deficiency ...
Coeliac disease is associated with other autoimmune diseases, including diabetes mellitus type 1, IgA deficiency, thyroid disease, primary biliary cirrhosis, Sjogren's syndrome, and a skin condition known as dermatitis herpetiformis.
Progression ...
HIV (human immunodeficiency virus) and AIDS (acquired immunodeficiency syndrome)
X-linked agammaglobulinemia
Selective IgA deficiency
Wiskott-Aldrich syndrome
Chronic granulomatous disease
Leukocyte adhesion defects
Bruton disease ...
First-degree relatives (children, siblings) of a person with celiac disease
Down syndrome
Type 1 diabetes
Selective IgA deficiency
Turner syndrome
Williams syndrome
Autoimmune thyroiditis ...
Although no clear proof of genetic influence on disease occurrence exists, the disease does occur in siblings. Additionally, family members have a higher incidence of hypogammaglobulinemia, selective IgA deficiency, and autoimmune disease.
Other rare genetic disorders associated with increased risk include Bloom syndrome, Fanconi's anemia, ataxia-telangiectasia, neurofibromatosis, Shwachman syndrome, IgA deficiency, and congenital X-linked agammaglobulinemia.
Other rare genetic disorders associated with increased risk include Klinefelter syndrome, Bloom syndrome, Fanconi anemia, ataxia-telangiectasia, neurofibromatosis, Shwachman syndrome, IgA deficiency, and congenital X-linked agammaglobulinemia.
Abnormalities of local immunological and nonimmunological defence mechanisms are important, especially in children; cystic fibrosis sinonasal manifestation, primary ciliary dyskinesia and IgA deficiency are the best known inherited diseases ...
Certain genetic disorders, such as Down's syndrome, Bloom syndrome, Fanconi's anemia, ataxia-telangiectasia, neurofibromatosis, Shwachman syndrome, IgA deficiency, and congenital X-linked agammaglobulinemia ...
The increased incidence of malignancies in HIV patients points to the breakdown of immune surveillance as a possible etiology of cancer. Certain other immune deficiency states (e.g. common variable immunodeficiency and IgA deficiency) are also ...
that as many as one in 20 insulin-dependent diabetics may have celiac disease. Patients with other conditions in which celiac disease may be more commonly found include those with juvenile chronic arthritis, some thyroid diseases, and IgA deficiency.
 See also: Deficiency, Symptom, Fusion, AIDS, Common variable immunodeficiency
  
|
RSS
