Leukocyte esterase is a screening test used to detect a substance that suggests there are white blood cells in the urine, which may mean you have a urinary tract infection.
The leukocyte esterase (LE) dipstick test is used to screen for pyuria (presence of pus in the urine when voided). LE, an enzyme found in neutrophil granules, reacts with an impregnated reagent pad to produce a blue color within 2-5 minutes.
5. Urinary leukocyte esterase is a useful screening test for chlamydial and GC infections in asymptomatic men. The usefulness of other neutrophil enzyme (elastace, myeloperoxidase) studies of urine have been reported.
Leukocyte esterase (WBC esterase). Leukocyte esterase shows leukocytes (white blood cells [WBCs] Opens New Window) in the urine. WBCs in the urine may mean a UTI is present.
Ketones.
Consider the example of UTI as given in Table 3: Clinical Decision Making: Distribution of Test Results of a Hypothetical Leukocyte Esterase Test in a Cohort of 1000 Women With an Assumed 30% Prevalence of UTI, ...
As noted in the CDC 2006 guidelines for diagnosis and management of epididymitis,[8] evaluation includes first-void urine testing by dipstick for leukocyte esterase and/or microscopy looking for 10 or more WBCs per high-power field.
Leukocyte esterase - this is an enzyme of the immune system. High levels in the urine usually indicate inflammation.
Nitrites (nitrituria) - high amounts of nitrites in the urine usually mean there is an infection.
Precautions must be taken to avoid contaminating the urine specimen with bacteria from the external genitalia by first cleaning with a disinfectant and then obtaining a midstream specimen (clean catch); nitrites and leukocyte esterase will be ...
 See also: Urinary tract, Symptom, Urine culture, Kidney, Diabetes
  
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