Liver fibrosis (dose-related, often reversible)
Nausea
Possibly bone marrow suppression ...
Direct markers of liver fibrosis are also being evaluated, including a number of serum or urinary tests, which are thought to directly reflect the deposition or removal of extracellular matrix involved in formation of fibrous tissue in the liver.
The disease causes scarring or liver fibrosis leading to cirrhosis. Symptoms include abdominal pain, jaundice, swelling of the ankles or abdomen and enlargement of the liver or spleen. In severe cases bleeding from the gut or coma can occur.
ANTIFIBROTIC: a drug or other agent than prevents or reduces the development of liver fibrosis or cirrhosis.
ANTIGEN: any agent or substance that stimulates an immune response. Antigens are often foreign invaders such as bacteria or viruses.
In a cohort study of biopsy-proven CHC patients with moderate or severe liver fibrosis, patients were divided into two groups.
They may also have eye problems, skeletal abnormalities and liver fibrosis. Less than half of those diagnosed as children have cysts on their kidneys. Kidney failure usually occurs in the early teens as part of juvenile nephronophthisis.
The specific problems produced differ according to the particular abnormal synthesis involved. Common manifestations include ataxia; seizures; retinopathy; liver fibrosis; coagulopathies; failure to thrive; dysmorphic features (e.g.
In the United States, hepatitis C virus (HCV) is the most common chronic blood-borne infection, the most common cause of chronic liver disease contributing to progressive liver fibrosis, cirrhosis and liver cancer, ...
Liu C, Hu Y, Xu L, Liu C, Liu P. Effect of Fuzheng Huayu formula and its actions against liver fibrosis. Chin Med. 2009 Jun 29;4:12.
» Siemens Unveils Imaging and Laboratory Solutions for Managing Liver Health at EASL 2011
» Siemens Launches First Automated Standardized Direct Biomarker Panel for Liver Fibrosis - a Leading Indicator of Chronic Liver Disease ...
(a) Angiosarcoma of the liver; or
(b) osteolysis of the terminal phalanges of the fingers; or
(c) Sclerodermatous thickening of the skin of the hands; or
(d) Liver fibrosis due to exposure to vinyl chloride monomer ...
Fibrosis is the growth of scar tissue due to infection, inflammation, injury, or even healing. The overgrowth of scar tissue can occur in almost any organ. Fibrosis in the liver can inhibit the organ's proper functioning. Liver fibrosis is usually ...
in liver cells (hepatocytes), causing cell enlargement (fatty liver or steatosis) and sometimes damage to the cell (steatohepatitis). The damage is often minor although a small proportion of patients with steatohepatitis develop liver fibrosis and ...
pain is related to the liver, it may be caused by an inflammation of the liver, either a sudden inflammation or a flare-up of a longstanding condition. It can also be due to a liver abscess or a growth, swelling, scarring (cirrhosis), liver fibrosis, ...
It is, in effect, like a severe form of liver fibrosis. Many liver conditions can lead to cirrhosis, including NAFLD. Severe cirrhosis can lead to liver failure. (See separate leaflet called 'Cirrhosis').
 See also: Fibrosis, Symptom, Hepatitis, Cancer, Cirrhosis
  
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