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Macroglobulinemia

Disease MacroamylasemiaMacroglobulinemia of Waldenstrom

Macroglobulinemia of Waldenstrom
Alternate Names : Waldenstrom's macroglobulinemia, Macroglobulinemia - primary, Lymphoplasmacytic lymphoma
Definition ...

 


Macroglobulinemia of Waldenstrom
From Healthscout's partner site on breast cancer, MyBreastCancerNetwork.com ...

Macroglobulinemia of Waldenstrom is a cancer of the B lymphocytes (a type of white blood cell). It is associated with the overproduction of proteins called IgM antibodies.
Causes ...

Waldenstrom's macroglobulinemia; Macroglobulinemia - primary; Lymphoplasmacytic lymphoma
Waldenstroms
Antibodies ...

Macroglobulinemia
Waldenstroem's Macroglobulinemia
Waldenstrom's Syndrome
None ...

Waldenstrom macroglobulinemia (WM) is a type of non-Hodgkin lymphoma (NHL) that produces large amounts of an abnormal protein (called a macroglobulin). Another name for WM is lymphoplasmacytic lymphoma.

Waldenstrom macroglobulinemia (WM) is a rare, slow-growing, non-Hodgkin lymphoma caused by an overproduction of immunoglobulin M. It causes a thickening of the blood’s plasma.

Why choose Mayo Clinic for Waldenstrom macroglobulinemia
Expertise and experience. Mayo Clinic doctors from multiple specialties have extensive experience in treating Waldenstrom macroglobulinemia and offer coordinated services.

Who gets Waldenstrom's Macroglobulinemia?
WM is a relatively rare condition, accounting for approximately 2% of haematological malignancies.

Macroglobulinemia: An increase of one type of immunoglobulin referred to as macroglobulin. It differs from other immunoglobulin molecules in being five times the size of standard-sized immunoglobulin.

macroglobulinemia A condition in which the blood contains high levels of large proteins and is too thick to flow through small blood vessels. One type is Waldenström's macroglobulinemia, which is a type of cancer.

Macroglobulinemia
In macroglobulinemia, abnormal plasma cells build up in the bone marrow, lymph nodes, and spleen. They make too much M protein, which causes the blood to become thick. The lymph nodes, liver, and spleen may become swollen.

To diagnose macroglobulinemia, your doctor will do blood tests and, possibly, bone x-rays. If the results are abnormal, you may be referred to a hematologist, a doctor who specializes in diagnosing and treating bone marrow and blood disorders.

Waldenstrom macroglobulinemia can occur in younger people but is usually seen in people over age 65. The disease is more common among men than women and among whites than blacks.

Waldenström Macroglobulinemia: Q & A
More...
Prevention, Genetics, Causes
Information related to genetics, risk factors, and prevention ...

Waldenström macroglobulinemia
Wilms tumor (kidney cancer), childhood
References
A to Z List of Cancers National Cancer Institute ...

Waldenström's Macroglobulinemia
This section has been reviewed and approved by the Cancer.Net Editorial Board, 12/08
Cancer.Net Guide to Waldenström's Macroglobulinemia ...

Waldenström's macroglobulinemia, multiple myeloma, sickle cell anemia: CBC with differential count, other testing (eg, serum protein electrophoresis) as clinically indicated
Treatment ...

Waldenstrom's macroglobulinemia
An indolent (slow-growing) type of non-Hodgkin's lymphoma marked by abnormal levels of IgM antibodies in the blood and an enlarged liver, spleen, or lymph nodes. Also called lymphoplasmacytic lymphoma.

: Prognostic factors in Waldenström's macroglobulinemia: a report of 167 cases. J Clin Oncol 11 (8): 1553-8, 1993.
Vijay A, Gertz MA: Waldenström macroglobulinemia. Blood 109 (12): 5096-103, 2007.
Dimopoulos MA, Kyle RA, Anagnostopoulos A, et al.

Macroglobulinemia
Macroglossia
Macroglossia-Omphalocele-Visceromegaly Syndrome
Macrolides for pneumonia - Medication
Macrothrombocytopenia with Leukocyte Inclusions
macrothrombocytopenia, familial Bernard-Soulier type
Macugen - Medication ...

Macroglobulinemia - primary
Macroglobulinemia of Waldenstrom
Macular degeneration
Magnesium - low
Major depression
Major depression with psychotic features
Major depressive disorder
Malabsorption
Malaria
Male pattern baldness ...

macroglobulinemia. This is a serious disease of the plasma causing bleeding tendencies, weight loss, blurred vision, and disease of the lymph nodes.
multiple myeloma, or a tumor in the bone marrow
preeclampsia of pregnancy ...

Definition Waldenstrom's macroglobulinemia is a rare, chronic cancer of the immune system that is characterized by hyperviscosity, or thickening, of the blood.

An abnormal result may also be due to Waldenstrom's macroglobulinemia, chronic lymphocytic leukemia, or amyloidosis.
Considerations
Urine immunofixation is the best test for detecting Bence-Jones proteins.

Lymphoma
Waldenstrom's Macroglobulinemia
Hairy cell Leukemia
more about Chronic Lymphocytic Leukemia ...

Multiple myeloma
Waldenström's macroglobulinemia
Heavy chain disease
Cancer Information: Classifying Hematological Disease ...

Pathogenesis and morbidity of autoantibody syndromes in Waldenstrom's macroglobulinemia.… more…
Autoimmune Cytopenia in Chronic… ...

Treatment and prognosis of Waldenstrom macroglobulinemia
Treatment of advanced stage (IIB to IV) mycosis fungoides and Sézary syndrome
Treatment of early stage (IA to IIA) mycosis fungoides
Treatment of hairy cell leukemia ...

Bone neoplasms
Chronic lymphocytic leukemia (plasma cell leukemia)
Metastatic cancer (carcinoma)
Monoclonal gammopathy of undetermined significance (MGUS)
Non-Hodgkin's lymphoma
Other protein disorders such as macroglobulinemia
Primary amyloidosis ...

Also called Waldenström macroglobulinemia.
Permalink for lymphoplasmacytic lymphoma
lymphopoietin-1 (LIM-foh-POY-eh-tin) One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body.

See also: Cancer, Lymphoma, Symptom, Myeloma, Multiple myeloma

Disease MacroamylasemiaMacroglobulinemia of Waldenstrom

 
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