Mast cell leukemia

Mast cell leukemia is an extremely aggressive subtype of acute myeloid leukemia that usually occurs de novo but can, rarely, evolve from transformation of chronic myeloid leukemia into the more aggressive acute myeloid leukemia.

Mast cell leukemia
Overview

Mast cell leukemia is the aggressive, terminal result of mast cell sarcoma and is a subtype of acute myeloid leukemia. It is also called aleukemic mast cell leukemia.

Mast cell leukemia, with > 20% mast cells in bone marrow, no skin lesions, multiorgan failure, and a poor prognosis
Symptoms and Signs ...

Stones, Common Bile Duct, Genes, Wilms Tumor, Genetically Modified Organisms, Inclusion-Body Disease, Atypical, Infectious Hepatitis, Canine, Inhibins, Leprosies, Tuberculoid, Loudness Perceptions, Low-Protein Diets, Ly 5 Antigen, Mast Cell Leukemia, ...

The risk of systemic mastocytosis becoming cancerous is 7% when disease begins in childhood, and as much as 30% in adults. Mast cell leukemia involves the blood, while mast cell sarcoma involves the soft tissues.

The following list shows these subtypes. Acute basophilic leukemia
Acute eosinophilic leukemia
Mast cell leukemia
Acute myeloid dendritic cell leukemia
Acute panmyelosis with myelofibrosis
Myeloid sarcoma.

For example, urticaria pigmentosa is a condition that arises from mast cells and is occasionally associated with mast cell leukemia; cutaneous T-cell lymphoma is often confined to the skin throughout its course.

See also: Leukemia, Sarcoma, Symptom, Mastocytosis, Systemic mastocytosis